1. Anti-infection
    Cell Cycle/DNA Damage
  2. Bacterial
    DNA/RNA Synthesis
  3. ACX-362E

ACX-362E 

Cat. No.: HY-128357
Handling Instructions

ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens.

For research use only. We do not sell to patients.

ACX-362E Chemical Structure

ACX-362E Chemical Structure

CAS No. : 1275582-97-2

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Description

ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens[1].

IC50 & Target

MIC50: 2 μg/mL (C. difficile)[1]

Molecular Weight

423.30

Formula

C₁₈H₂₀Cl₂N₆O₂

CAS No.

1275582-97-2

SMILES

O=C1NC(NCC2=CC=C(Cl)C(Cl)=C2)=NC3=C1N(CCN4CCOCC4)C=N3

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ACX-362E
Cat. No.:
HY-128357
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