13 Results for "

C5 Lenalidomide

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "C5 Lenalidomide" in MCE Product Catalog:

Cat. No.: HY-132248
CAS No.: 191732-70-4
Purity:  99.62%
Synonyms: Lenalidomide 5'-amine
Research Areas:  

Inflammation/Immunology

C5 Lenalidomide is a 5-amino-substituted Thalidomide (HY-14658) analog. C5 Lenalidomide inhibits LPS (HY-D1056)-stimulated TNF-α production .
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1 Cited Publications
Cat. No.: HY-P10899
Target:  

PROTACs TGF-beta/Smad

Research Areas:  

Endocrinology

ETTAC-2 is a LRG1 PROTAC degrader, degrading LRG1 via the ubiquitin-proteasome pathway with a DC50 value of 8.38 μM. ETTAC-2 penetrates damaged renal cells to reduce the extracellular secretion of LRG1. ETTAC-2 effectively inhibits the TGF-β-Smad3 signaling pathway and diminishes the secretion of fibrosis-associated extracellular matrix proteins. ETTAC-2 degrades LRG1 within fibrotic kidneys and the efficacy in inhibiting the TGF-β-Smad3 pathway both in vitro and vivo. ETTAC-2 can be used for renal fibrosis research .
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Cat. No.: HY-122725B
CAS No.: 2595367-27-2
Purity:  98.44%
Research Areas:  

Cancer

Lenalidomide-C5-NH2 hydrochloride is an E3 ligase ligand-linker conjugate. Lenalidomide-C5-NH2 hydrochloride can be coupled to a target protein ligand via a linker to form a PROTAC molecule—such as a PROTAC degrader for MDM2 .
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Cat. No.: HY-160241
CAS No.: 2338824-30-7
Research Areas:  

Cancer

Lenalidomide-C5-acid is the Lenalidomide-based E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Lenalidomide-C5-acid can be used to synthesize PROTACs .
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Cat. No.: HY-122725
CAS No.: 2093388-45-3
Research Areas:  

Others Cancer

Lenalidomide-C5-NH2 is an E3 ligase ligand-linker conjugate. Lenalidomide-C5-NH2 can be coupled to a target protein ligand via a linker to form a PROTAC molecule—such as a PROTAC degrader for MDM2 .
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Cat. No.: HY-129608
CAS No.: 2429878-72-6
Purity:  99.26%
Synonyms: Cereblon ligand-linker Conjugate
Research Areas:  

Cancer

Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC . Lenalidomide-acetylene-C5-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-132856
CAS No.: 2138441-25-3
Purity:  95.07%
Research Areas:  

Cancer

Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC .
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Cat. No.: HY-161132
CAS No.: 2399455-78-6
Research Areas:  

Others

Lenalidomide 4'-alkyl-C5-azide is a functionalized cerebellar ligand for PROTAC development that contains an E3 ligand and an alkyl LC5 ligand with terminal azides that can be coupled to a target protein ligand .
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Cat. No.: HY-W949165
CAS No.: 2883539-08-8
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

C5 Lenalidomide-6-fluoro is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. C5 Lenalidomide-6-fluoro can be linked to a target protein ligand via a linker to form a PROTAC.
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Cat. No.: HY-W586819
CAS No.: 2768326-37-8
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

C5 Lenalidomide-CH3 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. C5 Lenalidomide-CH3 can be linked to a target protein ligand via a linker to form a PROTAC.
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Cat. No.: HY-122725A
CAS No.: 2550398-71-3
Purity:  98.94%
Research Areas:  

Cancer

Lenalidomide-C5-NH2 TFA is an E3 ligase ligand-linker conjugate. Lenalidomide-C5-NH2 TFA can be coupled to a target protein ligand via a linker to form a PROTAC molecule—such as a PROTAC degrader for MDM2 .
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Cat. No.: HY-A0003S2
Synonyms: CC-5013-13C5,15N
Lenalidomide- 13C5, 15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
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Cat. No.: HY-W777286
CAS No.: 1219332-91-8
Synonyms: CC-5013-13C5
rac Lenalidomide- 13C5 is a 13C-labeled rac Lenalidomide .
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