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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
CXCL13
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "CXCL13" in MCE Product Catalog:
3
Target:
Research Areas:
3
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Cat. No.: HY-175606
CAS No.: 2588489-03-4
Target:
Research Areas:
EVT0185 is an orally active ATP citrate lyase (ACLY) inhibitor. EVT0185 is converted to a CoA thioester in the liver by SLC27A2 and interacts with the CoA-binding site of ACLY. EVT0185-CoA inhibits ACLY activity with an IC50 of 2.5 μM. EVT0185 can phenocopy the immune and antitumour effects of genetic ACLY deletion. EVT0185 can increase tumour-infiltrating B cells and chemokine CXCL13 levels. EVT0185 can be used for the research of cancer, such as hepatocellular carcinoma (HCC) .
Cat. No.: HY-P991567
Synonyms: VX5/5261
Target:
Research Areas:
Cat. No.: HY-RS03387
Target:
Research Areas:
CXCL13 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23036
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Research Areas:
Cxcl13 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcl13 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-163480
CAS No.: 2796997-12-9
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Research Areas:
Cat. No.: HY-RS16602
Target:
Research Areas:
Cxcl13 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcl13 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P992222
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Research Areas:
Cat. No.: HY-P992476
Cat. No.: HY-182774
CAS No.: 1092445-63-0
YU241279 is an orally active CXCR5 inhibitor. YU241279 inhibits CXCL13-mediated Gαq-dependent calcium influx and Gαi2-dependent cAMP reduction in CXCR5-expressing cells. YU241279 inhibits the proliferation of CXCR5-expressing lymphoma cells. YU241279 reduces tumor burden in the peripheral blood and bone marrow of mice implanted with lymphoma tissues. YU241279 is well tolerated during oral administration in mice, maintains stable plasma drug concentrations, and shows no metabolic changes. YU241279 can be used in the research of angioimmunoblastic T-cell lymphoma and Burkitt B-cell lymphoma .
Cat. No.: HY-P700234AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-X-C motif chemokine 13; BCA1; BLC; SCYB13
Cat. No.: HY-182671
CAS No.: 2409965-28-0
SRX3305 is an BTK/PI3K/BRD4 inhibitor with IC50s of 6.5 nM, 15 nM, and 4 nM toward BTK, PI3Kɑ and PI3Kδ, respectively. SRX3305 attenuates chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) cell proliferation and promotes apoptosis in a dose-dependent fashion. SRX3305 yields potent anti-tumor effects but spares healthy bystander cells. SRX3305 inhibits the activation-induced proliferation of primary CLL cells in vitro and effectively blocks microenvironment-mediated survival signals. SRX3305 blocks CLL cell migration toward CXCL-12 and CXCL-13. SRX3305 maintains its anti-tumor effects in Ibrutinib (HY-10997)-resistant CLL cells. SRX3305 can be used for research in CLL, diffuse large B-cell lymphoma (DLBCL) and MCL .
Cat. No.: HY-P700044AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13
Cat. No.: HY-P87311
Synonyms: ANGIE antibody; ANGIE2 antibody; B cell attracting chemokine 1 antibody; B cell-attracting chemokine 1 antibody; B lymphocyte chemoattractant antibody; B-cell chemoattractant antibody; B-cell-attracting chemokine 1 antibody; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1) antibody; BCA-1 antibody; BCA1 antibody
Cat. No.: HY-P76164
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-X-C motif chemokine 13; BCA1; BLC; SCYB13
Species:
Source:
Cat. No.: HY-P704362
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13
Cat. No.: HY-P700547
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
