2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Rosnilimab (Mouse IgG2a)

Rosnilimab (Mouse IgG2a) is a mouse-derived IgG2a, Rosnilimab. Rosnilimab is a PD-1 agonistic monoclonal antibody. Rosnilimab (Mouse IgG2a) can be used in research related to ulcerative colitis.

For research use only. We do not sell to patients.

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Based on 1 publication(s) in Google Scholar

Rosnilimab (Mouse IgG2a) Related Antibodies

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Description

Rosnilimab (Mouse IgG2a) is a mouse-derived IgG2a, Rosnilimab. Rosnilimab is a PD-1 agonistic monoclonal antibody. Rosnilimab (Mouse IgG2a) can be used in research related to ulcerative colitis[1].

Isotype

Mouse IgG2a kappa
Recommend Isotype Controls
Species Reactivity

Human
Gene ID

5133  [NCBI]

Accession
Target

PDCD1/PD-1/CD279
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

147.527 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Rosnilimab (Mouse IgG2a)]
Shipping

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Loaded Rosnilimab (Mouse IgG2a) on ProA biosensor, can bind HY-P7396 PD-1 Protein, Human (HEK293, His) with an affinity constant of 6.960E-10 M as determined in BLI assay.
Purity & Documentation
References
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Rosnilimab (Mouse IgG2a) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rosnilimab (Mouse IgG2a)PD-1/PD-L1PD-1/Programmed death-ligand 1monoclonal antibodyPD-1Mouse IgG2aPD-1 signalingulcerative colitisInhibitorinhibitorinhibit

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Rosnilimab (Mouse IgG2a)
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HY-P9S0062
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