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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
ChemR23
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "ChemR23" in MCE Product Catalog:
Target:
Research Areas:
ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro .
Cat. No.: HY-P6442
CAS No.: 1020407-90-2
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
Cat. No.: HY-P11273
CAS No.: 1610366-43-2
Synonyms: OK 101
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Synonyms: (-)-Resolvin E2
Research Areas:
Resolvin E2 ((-)-Resolvin E2) is an endogenous lipid mediator produced from eicosapentaenoic acid (EPA) under the catalysis of 5-lipoxygenase (5-LOX), and its production increases in hypoxic environments. Resolvin E2 antagonizes BLT1, partially activates ChemR23, and promotes ubiquitin-proteasome-mediated degradation of COX-2. Resolvin E2 reduces the production of prostaglandin E2, blocks polymorphonuclear leukocyte infiltration, and promotes the resolution of airway inflammation. Resolvin E2 ameliorates lipopolysaccharide (LPS) (HY-D1056)-induced depressive-like behaviors . Resolvin E2 can be used in research related to depression, murine peritonitis, neonatal asthma, and other conditions .
Cat. No.: HY-145922
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ChemR23 ligand-1 is a chemical probe that contributes to the elucidation and analysis of the functions of ChemR23.
Cat. No.: HY-147642
CAS No.: 2465085-23-6
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ChemR23-IN-4 (Compound 13) is a potent and orally efficacious ChemR23 inhibitor with an IC50 of 17 nM against human ChemR23 .
Cat. No.: HY-145352
CAS No.: 2465086-50-2
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ChemR23-IN-2 is a potent and orally efficacious ChemR23 inhibitor with an IC50 value of 3.2 nM.
Cat. No.: HY-145921
CAS No.: 3032433-98-7
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ChemR23-IN-3 is a potent thiazole-based ChemR23 inhibitor with an IC80 value of 12 nM.
Cat. No.: HY-P2712
CAS No.: 686324-96-9
Synonyms: Chemerin148–156, mouse
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Cat. No.: HY-RS02860
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CMKLR1 Human Pre-designed siRNA Set A contains three designed siRNAs for CMKLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16979
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Cmklr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cmklr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702250
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CMKLR1; G-Protein Coupled Receptor DEZ; Chemerin Chemokine-Like Receptor 1; Resolvin E1 Receptor; Chemokine-Like Receptor 1; Chemerin Receptor; Chemerin-Like Receptor 1; DEZ; ChemR23; Orphan G-Protein Coupled Receptor, Dez; RVER1; Chemokine Receptor-Like
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
