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Cat. No.: HY-147642

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ChemR23-IN-4

ChemR23-IN-4 (Compound 13) is a potent and orally efficacious ChemR23 inhibitor with an IC₅₀ of 17 nM against human ChemR23.

For research use only. We do not sell to patients.

CAS No.: 2465085-23-6
Formula: C₂₇H₂₆N₆O₃
Molecular Weight:482.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

ChemR23-IN-4 Chemical Structure

CAS No.: 2465085-23-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ChemR23-IN-4 (Compound 13) is a potent and orally efficacious ChemR23 inhibitor with an IC₅₀ of 17 nM against human ChemR23^[1].

IC₅₀ & Target

IC₅₀: 17 nM (hChemR23)^[1]

All Chemerin Receptor Isoforms :

ChemR23/CMKLR1

Chemical Information

CAS No. 2465085-23-6
Molecular Weight 482.53
Formula C₂₇H₂₆N₆O₃
SMILES

CCCCN([C@@H](C1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)C)C4=NC5=C(O4)C=CC=C5C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Imaizumi T, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ChemR23-IN-4

All Chemerin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ChemR23-IN-4 Related Classifications

HY-147642 Related Classifications