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Cat. No.: HY-145921

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ChemR23-IN-3

ChemR23-IN-3 is a potent thiazole-based ChemR23 inhibitor with an IC₈₀ value of 12 nM.

For research use only. We do not sell to patients.

CAS No.: 3032433-98-7
Formula: C₃₁H₃₃N₅O₅S₂
Molecular Weight:619.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

ChemR23-IN-3 Chemical Structure

CAS No.: 3032433-98-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ChemR23-IN-3 is a potent thiazole-based ChemR23 inhibitor with an IC₈₀ value of 12 nM.

All Chemerin Receptor Isoforms :

ChemR23/CMKLR1

Chemical Information

CAS No. 3032433-98-7
Molecular Weight 619.75
Formula C₃₁H₃₃N₅O₅S₂
SMILES

CC1=CC=C(C(NO2)=NC2=O)C(C(C=C3)=CC=C3[C@@H](C)N(CC4CC4)C5=NC(C(NS(C6CC6)(=O)=O)=O)=C(C7CC7)S5)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Imaizumi T, et al. Discovery and mechanistic study of thiazole-4-acylsulfonamide derivatives as potent and orally active ChemR23 inhibitors with a long-acting effect in cynomolgus monkeys. Bioorg Med Chem. 2022 Feb 15;56:116587. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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References

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ChemR23-IN-3

All Chemerin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ChemR23-IN-3 Related Classifications

HY-145921 Related Classifications