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Cat. No.: HY-145922

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ChemR23 ligand-1

ChemR23 ligand-1 is a chemical probe that contributes to the elucidation and analysis of the functions of ChemR23.

For research use only. We do not sell to patients.

Formula: C₉₇H₁₁₅ClN₁₂O₂₀S₂
Molecular Weight:1868.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

ChemR23 ligand-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ChemR23 ligand-1 is a chemical probe that contributes to the elucidation and analysis of the functions of ChemR23.

Chemical Information

Molecular Weight 1868.60
Formula C₉₇H₁₁₅ClN₁₂O₂₀S₂
SMILES

C[C@@H](N(C1=NC(C(NS(=O)(C2CC2)=O)=O)=C(S1)C3CC3)CC4CC4)C5=CC=C(C=C5)C6=C(C=CC(Cl)=C6)C(NCCOCCOCCOCCOCCOCCOCCN7N=NC8=C7C9=C(N(CC%10=C8C=CC=C%10)C(CCNC(CCOCCOCCOCCOCCNC(C%11=CC=C(C(C%12=C%13C=C/C(C=C%13OC%14=C%12C=CC(N(C)C)=C%14)=[N+](C)/C)=C%11)C([O-])=O)=O)=O)=O)C=CC=C9)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Imaizumi T, et al. Discovery and mechanistic study of thiazole-4-acylsulfonamide derivatives as potent and orally active ChemR23 inhibitors with a long-acting effect in cynomolgus monkeys. Bioorg Med Chem. 2022 Feb 15;56:116587. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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