23 Results for "

Complement C3 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "Complement C3 Antibody" in MCE Product Catalog:

Cat. No.: HY-P99050
CAS No.: 2049079-64-1
Synonyms: BIVV009; IPN-009; TNT009

Target:  

Complement System

Research Areas:  

Endocrinology

Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s). Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome .
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Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR 445088
Riliprubart (SAR 445088) is a selective anti-C1s humanized IgG4 monoclonal antibody with mutations that enhance its binding to the neonatal Fc receptor. Riliprubart blocks activation of the classical complement pathway, prevents the formation of the C3 convertase C4b2a, and inhibits complement-mediated hemolytic activity. Riliprubart can be used in research related to classical complement-mediated diseases, cold agglutinin disease, and chronic inflammatory demyelinating polyneuropathy. For the isotype control of Riliprubart, refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990025
CAS No.: 2579031-19-7
Synonyms: ARGX-117

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .
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Cat. No.: HY-P990637

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

NGM-621 is a CHO-expressed human antibody that targets Complement C3. NGM-621 contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 149.04 kDa. The isotype control for NGM-621 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097

Target:  

CD3 Complement System

Research Areas:  

Inflammation/Immunology

Ebribafusp alfa (ADX-097) comprising a humanized anti-C3d monoclonal antibody linked to two moieties of the first five consensus repeats of factor H (fH1-5). Ebribafusp alfa binds C3d and related fragments, catalyzes AP convertase dissociation, acts as a factor I co-factor for C3b cleavage, and delivers fH1-5 moieties to C3d-deposited tissues for local complement inhibition without systemic blockade. Ebribafusp alfa reduces glomerular C3 deposition, proteinuria, urine albumin-creatinine ratios, and urine soluble C5b-9 levels, preserves podocyte foot-process architecture, inhibits skin complement activation, and localizes to UVB-damaged primate skin. Ebribafusp alfa can be used for the research of membranous nephropathy, bullous pemphigoid, discoid lupus erythematosus, C3 glomerulopathy, IgA nephropathy, and lupus nephritis .
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Cat. No.: HY-P80577
Synonyms: AHUS5; ARMD9; ASP; Complement C3; Complement factor 3; CPAMD1; HEL S 62p

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P992456

Target:  

Complement System

SAR-443809 is a monoclonal antibody targeting complement factor Bb that inhibits the alternative complement pathway. SAR-443809 blocks the cleavage of C3 and factor B via selective binding to the activated form factor Bb, with a KD of 7.3 nM for human factor Bb. SAR-443809 inhibits the amplification loop of the alternative complement pathway and C3 activation, reduces C3b deposition, and blocks the activation of pathways associated with intravascular and extravascular hemolysis. SAR-443809 can be used for research on hematological and renal disorders mediated by abnormal alternative complement pathway activity .
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Cat. No.: HY-P80577A
Synonyms: AHUS5; ARMD9; ASP; Complement C3; Complement factor 3; CPAMD1; HEL S 62p

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P87306
Synonyms: Acidic C4 Antibody; Acidic Complement C4 Antibody; Basic C4 Antibody; Basic Complement C4 Antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 Antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 Antibody; C4, Chido form Antibody; C4, Rodgers from Antibody; C4A anaphylatoxin Antibody; C4A Antibody

Host:  

Rabbit

Application:  

WB, ICC/IF, IF-Tissue, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P810739
Synonyms: CO4; CPAMD3; ; Complement C4-B; Basic Complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86840
Synonyms: Complement C5 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 Complement C5 beta chain Complement C5 alpha chain C5a anaphylatoxin Complement C5 alpha' chain C5 CPAMD4

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human

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Cat. No.: HY-P810737
Synonyms: CO4, CPAMD3, C4B_2, C4B, Complement C4-B, Basic Complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P85085
Synonyms: ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD antigen CD18

Host:  

Mouse

Application:  

ICC/IF, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P80795
Synonyms: ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD antigen CD18

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80795A
Synonyms: ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD antigen CD18

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85894
Synonyms: C3 binding protein; C3b/C4b receptor; C3BR; C4BR; CD 35; CD35; CD35 antigen; Complement component; 3b/4b; receptor 1; Knops blood group; Complement component; 3b/4b; receptor 1 including Knops blood group system; Complement component receptor 1; Complement receptor 1; Complement receptor type 1; CR 1; CR1; CR1_HUMAN; KN; Knops blood group antigen

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P83239
Synonyms: C3/C5 convertase; Complement factor B; PBF2; Properdin factor B

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P810367
Synonyms: C3/C5 convertase, Complement factor B, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Rat

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Cat. No.: HY-P86464
Synonyms: CR2; C3DR; Complement receptor type 2; Cr2; Complement C3d receptor; Epstein-Barr virus receptor; EBV receptor; CD21

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81583
Synonyms: C3BR,Complement receptor type 1,C3b/C4b receptor,CD35

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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