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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
DNA aptamer
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "DNA aptamer" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W073524
CAS No.: 1420815-55-9
Cat. No.: HY-148826
CAS No.: 145563-68-4
Synonyms: ARC 183; BC 007
Domaines de recherche:
Rovunaptabin (ARC 183) is an aptamer, a single-stranded DNA molecule composed of 15 deoxynucleotides. It acts as a broad-spectrum neutralizer of pathogenic G-protein-coupled receptor autoantibodies. Rovunaptabin can be used in research related to cardiomyopathy and pulmonary hypertension .
Cat. No.: HY-160066
Target:
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SYL3C aptamer sodium is a DNA aptamer targeting EpCAM. SYL3C aptamer sodium targets a variety of cancer cell lines. SYL3C aptamer sodium can be used for targeted cancer cell imaging and circulating tumor cell detection .
Cat. No.: HY-177119
Target:
Domaines de recherche:
ZBP1 Covalent PROTAC-1 is a covalent PROTAC degrader targeting ZBP1, with a DC50 of 25.69 nM. ZBP1 Covalent PROTAC-1 integrates a ZBP1-binding DNA aptamer, a linker containing covalent NASA, and an E3 ligase-recruiting moiety to guide ubiquitin-proteasome system-mediated degradation of ZBP1. ZBP1 Covalent PROTAC-1 exhibits inhibitory activity against necroptosis signaling pathways and inflammatory responses. ZBP1 Covalent PROTAC-1 can be used for research on viral pneumonia .
Cat. No.: HY-177655A
Synonyms: Fovista sodium
Pegpleranib (Fovista) sodium is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.
Cat. No.: HY-160596
CAS No.: 2409156-19-8
Synonyms: 5-Formyl-deoxycytidine lithium
Target:
Domaines de recherche:
5-Formyl-dCTP (5-Formyl-deoxycytidine) lithium is a DCTPP1 substrate. 5-Formyl-dCTP lithium acts as a mutagen/epigenetic disruptor via DNA polymerase incorporation, mutagenic mispairings, and disturbed epigenetic programming. 5-Formyl-dCTP lithium can be used for research on genotoxicity .
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DNA, 5'-TAACACGACAGACGTTCGGAGGTCGAACCCTGACAGCGTGGGC-3', sodium salt
Cat. No.: HY-160050
Cat. No.: HY-177406
Target:
Domaines de recherche:
VR11 aptamer is a DNA-based TNF-α inhibitor with a KD of 7.0 nM. VR11 aptamer prevents TNFα-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research .
Cat. No.: HY-160045
Target:
Domaines de recherche:
AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo .
Cat. No.: HY-177807
Target:
Domaines de recherche:
DNMT1 aptamer sodium is a DNA aptamer for binding and inhibition of DNA methyltransferase 1 (DNMT1).
Cat. No.: HY-177655
CAS No.: 1618657-13-8
Synonyms: Fovista
Pegpleranib (Fovista) is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.
Target:
Domaines de recherche:
Cat. No.: HY-177804
Target:
Domaines de recherche:
Thrombin aptamer is a 11mer-DNA aptamer that targets thrombin. Thrombin aptamer inhibites thrombin-catalysed fibrin-clot formation in vitro
Cat. No.: HY-177637
Target:
Domaines de recherche:
H5N1 aptamer sodium is a DNA aptamer targeted to H5N1 Avian Influenza Virus.
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DNA, 5'-CCTAACTGAGCTGTACTCGACTTATCCCGGATGGGGCTCTTAGG-3', sodium salt
Cat. No.: HY-177803
Cat. No.: HY-160063
Domaines de recherche:
SW1 aptamer sodium is a high-affinity DNA aptamer (Kd: 123.62 nM) that targets liver cancer SMMC-7721 cells and targets intracellular components within the nucleus. SW1 aptamer sodium can also identify various other types of cancer cells and tissues, serving as an effective molecular probe for clinical cancer diagnosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
