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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
ELOVL6
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "ELOVL6" in MCE Product Catalog:
6
6 Cited Publications
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ELOVL6-IN-2 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-2 inhibits mouse ELOVL6 activities, with an IC50 value of 34 nM .
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ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor with IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-4 shows excellent selectivity over the other human ELOVL subtypes (ELOVL1, -2, -3, and -5) and mouse ELOVL3 .
Cat. No.: HY-160912
CAS No.: 1135000-36-0
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ELOVL6-IN-5 is an orally active and selective elongase enzyme of long-chain fatty acid family 6 (ELOVL6) inhibitor with IC50 values of 85 nM and 38 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-5 shows >60-fold selectivity over other ELOVL family enzymes (ELOVL1, 2, 3, 5) and no effect on other lipid synthesis enzymes like ACC1, ACC2. ELOVL6-IN-5 reduces hepatic fatty acid composition ratio of C18 to C16 in diet-induced obesity (DIO) and KKAy mice. ELOVL6 inhibition by ELOVL6-IN-5 does not improve insulin resistance. ELOVL6-IN-5 can be used for the research of metabolic disease .
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ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA .
Cat. No.: HY-N11011
CAS No.: 57423-72-0
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Cat. No.: HY-RS04326
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ELOVL6 Human Pre-designed siRNA Set A contains three designed siRNAs for ELOVL6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24566
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Elovl6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Elovl6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18092
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Elovl6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Elovl6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P810996
Synonyms: FACE, LCE, ELOVL6, Very long chain fatty acid elongase 6, 3-keto acyl-CoA synthase ELOVL6, ELOVL fatty acid elongase 6, Elongation of very long chain fatty acids protein 6, Fatty acid elongase 2, Fatty acyl-CoA elongase, Long-chain fatty-acyl elongase, Very long chain 3-ketoacyl-CoA synthase 6, Very long chain 3-oxoacyl-CoA synthase 6, ELOVL FA elongase 6, hELO2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
