712346-06-0
712346-06-0
Chemical Structure
ELOVL6-IN-1
- CAS No.: 712346-06-0
- Formula:C27H24F3N3O3
- Molecular Weight:495.49
IUPAC Name: 6,6-dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
InChIKey: XNUIQJWHESYIAP-UHFFFAOYSA-N
SMILES: O=C1C(C2(C(F)(F)F)C(N(C3=C2C(CC(C)(C3)C)=O)C4=CC=CC=C4)=O)=C(C)NN1C5=CC=CC=C5
Biological Activity: ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ELOVL6-IN-1 | 99.19% | ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA. | ||||||||||||||||||||
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