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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Elastase substrate
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Elastase substrate" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P4476
CAS No.: 72682-69-0
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Cat. No.: HY-P2685
CAS No.: 70967-90-7
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Cat. No.: HY-137409
CAS No.: 52299-14-6
Cat. No.: HY-P3106
CAS No.: 149695-85-2
Synonyms: (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110
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Cat. No.: HY-P5374
CAS No.: 125791-90-4
Cat. No.: HY-P4126
CAS No.: 113277-37-5
Cat. No.: HY-126785
CAS No.: 108392-27-4
Synonyms: Colorimetric Elastase substrate
Cat. No.: HY-P5459
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Elafin(human) is a serine protease inhibitory peptide that potently inhibits human neutrophil elastase (HLE) and human proteinase 3 (PR3). Elafin(human) forms a substrate-like, competitive and fully reversible complex with HLE at a 1:1 stoichiometric ratio, with a Ki of 0.17 nM. Elafin(human) inhibits PR3-mediated degradation of elastin-FITC, with an IC50 of 9.5 nM. Elafin(human) can be used in studies of neutrophil serine proteases, elastin degradation and inflammation-related tissue damage
Cat. No.: HY-136705
CAS No.: 111682-13-4
Synonyms: MSACK
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MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE), with an IC50 of 20.3 μM. MeO-Suc-Ala-Ala-Pro-Ala-CMK can inhibit the hydrolysis of substrates such as elastin in lung tissue by HNE. MeO-Suc-Ala-Ala-Pro-Ala-CMK can be used in the research of related diseases such as chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-169324
CAS No.: 2921735-91-1
Synonyms: Mal-Exo-EEVC-Exatecan
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APL-1092 is an EEVC linker-payload conjugate composed of exatecan, a stabilizer that prevents premature payload release, and a cleavage substrate for cathepsin B . APL-1092 resists premature payload release mediated by human neutrophil elastase and carboxylesterase, maintains payload stability in mouse plasma, and retains cathepsin B-mediated cleavage activity in target cells . APL-1092 exhibits dose-dependent tumor growth inhibition in xenograft mice . APL-1092 can be used in gastric cancer-related research .
Cat. No.: HY-P5993
CAS No.: 72252-91-6
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Cat. No.: HY-P4350
CAS No.: 73617-90-0
Cat. No.: HY-P4362
CAS No.: 88467-44-1
Cat. No.: HY-P4489
CAS No.: 72682-73-6
Cat. No.: HY-P4346
CAS No.: 201853-55-6
Cat. No.: HY-125128
CAS No.: 83329-36-6
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Cat. No.: HY-16707
CAS No.: 252557-97-4
Synonyms: Z-Ile-Glu-Pro-Phe-Ome
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Neutrophil elastase-IN-7 (Compound 12) is an effective inhibitor of neutrophil elastase (HNE), with an IC50 value of 0.54 μM. Neutrophil elastase-IN-7 also exhibits significant inhibitory activity against various coagulation proteins, with the IC50 values for thrombin, FXa, FXIa, and FXIIIa being 8.2, 12.7, 1.2, and 5.7 μM, respectively. Neutrophil elastase-IN-7 can be used for research on inflammation, innate immune responses, and tissue remodeling .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
