108392-27-4
Chemical Structure
Suc-AAP-Abu-pNA
Synonym(s): Colorimetric Elastase Substrate
- CAS No.: 108392-27-4
- Formula:C25H34N6O9
- Molecular Weight:562.57
IUPAC Name: 4-(((S)-1-(((S)-1-((S)-2-(((S)-1-((4-nitrophenyl)amino)-1-oxobutan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)amino)-4-oxobutanoic acid
InChIKey: SSDBXDGLQPOZGD-LNMJFAINSA-N
SMILES: OC(CCC(N[C@@H](C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CC)C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O)=O)=O
Biological Activity: Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration[1].
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Suc-AAP-Abu-pNA | Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration. | |||||||||||||||||||||
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Keywords
