111682-13-4
Chemical Structure
MeO-Suc-Ala-Ala-Pro-Ala-CMK
Synonym(s): MSACK
- CAS No.: 111682-13-4
- Formula:C20H31ClN4O7
- Molecular Weight:474.94
IUPAC Name: methyl 4-(((S)-1-(((S)-1-((S)-2-(((S)-4-chloro-3-oxobutan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)amino)-4-oxobutanoate
InChIKey: UIYRKMRXXFXSTH-XUXIUFHCSA-N
SMILES: O=C(N[C@@H](C)C(CCl)=O)[C@H]1N(C([C@H](C)NC([C@H](C)NC(CCC(OC)=O)=O)=O)=O)CCC1
Biological Activity: MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE), with an IC50 of 20.3 μM. MeO-Suc-Ala-Ala-Pro-Ala-CMK can inhibit the hydrolysis of substrates such as elastin in lung tissue by HNE. MeO-Suc-Ala-Ala-Pro-Ala-CMK can be used in the research of related diseases such as chronic obstructive pulmonary disease (COPD)[1].
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MeO-Suc-Ala-Ala-Pro-Ala-CMK | MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE), with an IC50 of 20.3 μM. MeO-Suc-Ala-Ala-Pro-Ala-CMK can inhibit the hydrolysis of substrates such as elastin in lung tissue by HNE. MeO-Suc-Ala-Ala-Pro-Ala-CMK can be used in the research of related diseases such as chronic obstructive pulmonary disease (COPD). | |||||||||||||||||||||
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