48 Results for "

Enkephalins

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "Enkephalins" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P0288
CAS No.: 58822-25-6
Synonyms: Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin
[Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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1
1 Cited Publications
Cat. No.: HY-105343
CAS No.: 63631-40-3
Purity:  99.92%
Synonyms: [D-Ala2, D-Leu5]-Enkephalin; DADLE
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

BW-180C ([D-Ala2, D-Leu5]-Enkephalin; DADLE) is an δ opioid receptor (DOR) agonist, which belongs to the enkephalin family. Neuroprotective agent. BW-180C reversibly inhibits cellular transcription in neurons without causing cell injury .
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1
1 Cited Publications
Cat. No.: HY-P4270
CAS No.: 67368-29-0
Target:  

Neprilysin

Research Areas:  

Neurological Disease

Met-Arg-Phe-Ala is a peptide. Met-Arg-Phe-Ala also is a potent competitive inhibitor for enkephalin-generating endopeptidase (EGE). Met-Arg-Phe-Ala can be used for the research of neurological disease .
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Cat. No.: HY-W345510
CAS No.: 864084-88-8
Target:  

Neprilysin

Research Areas:  

Neurological Disease

Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC50 value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission .
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Cat. No.: HY-P0098
CAS No.: 64963-01-5
[D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.
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Cat. No.: HY-P1701
CAS No.: 74135-04-9
Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for Enkephalin receptors .
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Cat. No.: HY-P1470
CAS No.: 60117-24-0
Synonyms: Leu-Enkephalin amide
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[Leu5]-Enkephalin, amide is a δ opioid receptor agonist.
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Cat. No.: HY-P3513
CAS No.: 77739-21-0
Target:  

ERK MMP

Research Areas:  

Neurological Disease

β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9 .
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Cat. No.: HY-118120
CAS No.: 77482-44-1
Synonyms: 2-Guanidinoethylmercaptosuccinic acid
Target:  

Carboxypeptidase

Research Areas:  

Neurological Disease

GEMSA is a potent inhibitor of enkephalin convertase (Ki=8.8 nM). GEMSA elicites analgesia .
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Cat. No.: HY-P1170
CAS No.: 2703746-32-9
Synonyms: Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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Cat. No.: HY-P1467A
CAS No.: 2918768-28-0
Synonyms: 5-Methionine-enkephalin amide TFA
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[Met5]-Enkephalin, amide TFA is an agonist for δ opioid receptors as well as putative ζ ζ opioid receptors.
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Cat. No.: HY-W048697
CAS No.: 201532-01-6
Research Areas:  

Others

Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
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Cat. No.: HY-117702
CAS No.: 135949-60-9
RB 101 is a blood-brain barrier-crossing prodrug as well as aminopeptidase N and neutral endopeptidase-24.11 inhibitor. RB 101 blocks enkephalin breakdown, elevates extracellular enkephalin levels and activate δ-opioid receptor and dopamine D1 receptor. RB 101 can be used for the research of pain, depressive syndromes, and diabetic neuropathy .
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Cat. No.: HY-P3546
CAS No.: 88373-72-2
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[DPen2, Pen5] Enkephalin is a δ-opioid receptor selective analog of [Leu5]-Enkephalin (HY-P0288) .
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Cat. No.: HY-P2626
CAS No.: 61370-87-4
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[D-Ala2]-Met-Enkephalin, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalin inhibits ACh-induced and suckling-induced oxytocin (OT) release .
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Cat. No.: HY-P1044
CAS No.: 137201-62-8
Synonyms: LVV-hemorphin-4
Target:  

Carboxypeptidase

Research Areas:  

Neurological Disease

Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect .
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Cat. No.: HY-P1044A
CAS No.: 2828433-21-0
Synonyms: LVV-hemorphin-4 TFA
Target:  

Angiotensin Receptor

Research Areas:  

Neurological Disease

Spinorphin TFA is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect .
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Cat. No.: HY-P3962
CAS No.: 34783-35-2
Research Areas:  

Endocrinology

[Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin .
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Cat. No.: HY-P2828
CAS No.: 80943-05-1
Research Areas:  

Others

[Des-Pro2]-Bradykinin is a protease inhibitor. [Des-Pro2]-Bradykinin prevents the degradation of methionine enkephalin .
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Cat. No.: HY-115500
CAS No.: 1206514-50-2
PL265 is an orally active dual enkephalinase inhibitor. PL265 is a prodrug of PL254, which can simultaneously and efficiently inhibit neutral endopeptidase (Neprilysin) and Aminopeptidase N. PL265 can effectively protect and significantly increase the local concentration of enkephalins (such as Met-Enkephalin and Leu-Enkephalin) released by cells at the pain or inflammation sites, thereby activating μ and δ opioid receptors to produce a potent analgesic effect. PL254 can also inhibit leukotriene A4 hydrolase (LTA4H), which may contribute to its additional anti-inflammatory effect by reducing the production of pro-inflammatory mediator leukotriene B4 (LTB4). PL265 can be used in non-addictive chronic pain research .
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