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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
FFAR4
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "FFAR4" in MCE Product Catalog:
1
Category:
Target:
Domaines de recherche:
Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis [4].
Cat. No.: HY-RS04877
Target:
Domaines de recherche:
FFAR4 Human Pre-designed siRNA Set A contains three designed siRNAs for FFAR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-162689
Target:
Domaines de recherche:
GprA is a new synthetic agonist of G-protein-coupled receptor 120/free fatty acid receptor 4 (GPR120/FFAR4), with an AC50 of 203 nM on human GPR120 full isoform. GprA can be used in the research for NAFLD .
Cat. No.: HY-N3977
CAS No.: 80557-12-6
Target:
Cat. No.: HY-RS18817
Target:
Domaines de recherche:
Ffar4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ffar4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164870
CAS No.: 2839486-16-5
Target:
Domaines de recherche:
FFAR1/FFAR4 agonist-1 (compound 83) is a FFAR1/FFAR4 agonist with the EC50 of 1 nM A and 4nM for FFAR1 and FFAR4, respectively. FFAR1/FFAR4 agonist-1 can be used for study of glycemic control .
Cat. No.: HY-185937
CAS No.: 3110207-82-1
Target:
Domaines de recherche:
FFAR4 agonist-1 is an orally active, selective agonist of FFAR4. FFAR4 agonist-1 improves glucose tolerance, reduces blood glucose levels and promotes insulin secretion. FFAR4 agonist-1 can be used in the research of type 2 diabetes .
Cat. No.: HY-RS25307
Target:
Domaines de recherche:
Ffar4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ffar4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W592871R
CAS No.: 765-01-5
Synonyms: 10-HDA (Standard); Queen Bee Acid (Standard)
Category:
Target:
Cat. No.: HY-121212R
CAS No.: 1253909-57-7
Domaines de recherche:
Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis [4].
Cat. No.: HY-182921
Target:
Domaines de recherche:
GPR84 antagonist 11 is a highly selective GPR84 antagonist, with a human pA2 of 8.41 and a pKi of 8.16. GPR84 antagonist 11 competitively inhibits the binding of agonists to the orthosteric site of GPR84 and has improved druglike properties, though its metabolic stability still requires optimization. GPR84 antagonist 11 can be used in the research of autoimmune diseases and fibrotic diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
