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Results for "

Fas (CD95)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Caspase (1)
By Research Areas:	Cancer (1) Metabolic Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: FASTK CD1 CD38 CD28 CD19 CD20 CD22 Transferrin Receptor CD3 P-selectin CD6 CD2 CD276/B7-H3 CD73 c-Kit LAG-3 L-Selectin CTLA-4 CD47 ALCAM/CD166 Neprilysin E-Selectin Scavenger Receptor Class B type I (SR-BI） FLT3 Tim3 CD44 Anaplastic lymphoma kinase (ALK) CD74 Human leukocyte immunoglobulin (Ig)-like receptors (LILR) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108610C

(S)-Edelfosine (S)-ET-18-OCH3	Apoptosis	Cancer
(S)-Edelfosine ((S)-ET-18-OCH3) is the (S)-enantiomer of Edelfosine (ET-18-OCH3) (HY-108610C). Edelfosine is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor .

HY-P992072

*Anti-Human/Mouse CD95* Antibody (HFE7A)**	Apoptosis Caspase	Metabolic Disease
Anti-Human/Mouse CD95 Antibody (HFE7A) is an antibody targeting human/mouse **Fas (CD95), with a K_d** of 1.6 nM in mice. Anti-Human/Mouse CD95 Antibody (HFE7A) modulates the *Fas*-mediated apoptotic signaling pathway without blocking the binding of Jo2 to *Fas. Anti-Human/Mouse CD95* Antibody (HFE7A) inhibits Jo2-induced caspase activation, mitochondrial depolarization, hepatocyte death and apoptosis. Anti-Human/Mouse CD95 Antibody (HFE7A) protects BALB/c mice against Jo2-induced acute liver injury and reduces Jo2-associated elevation of serum transaminase levels. Anti-Human/Mouse CD95 Antibody (HFE7A) can be used in studies related to liver injury. For isotype control, refer to Mouse IgG1 kappa, Isotype Control (HY-P99977) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992072

*Anti-Human/Mouse CD95* Antibody (HFE7A)**	Apoptosis Caspase	Metabolic Disease
Anti-Human/Mouse CD95 Antibody (HFE7A) is an antibody targeting human/mouse **Fas (CD95), with a K_d** of 1.6 nM in mice. Anti-Human/Mouse CD95 Antibody (HFE7A) modulates the *Fas*-mediated apoptotic signaling pathway without blocking the binding of Jo2 to *Fas. Anti-Human/Mouse CD95* Antibody (HFE7A) inhibits Jo2-induced caspase activation, mitochondrial depolarization, hepatocyte death and apoptosis. Anti-Human/Mouse CD95 Antibody (HFE7A) protects BALB/c mice against Jo2-induced acute liver injury and reduces Jo2-associated elevation of serum transaminase levels. Anti-Human/Mouse CD95 Antibody (HFE7A) can be used in studies related to liver injury. For isotype control, refer to Mouse IgG1 kappa, Isotype Control (HY-P99977) .

Recombinant Proteins Recommended:

Fas/CD95

Species:	Human (10) Rat (2) Mouse (4) Cynomolgus (2)
Tag:	His (11) Tag Free (3) Fc (4)
Source:	HEK293 (11) P. pastoris (3) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78296

	Fas/CD95 Protein, Mouse (HEK293, Fc) FasLG receptor; CD95; APT1; Fas1; TNFRSF6; Fas; ALPS1A; APO1; FasTM; FasR	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, Fc) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal hFc-tag.

HY-P7169

	Fas/CD95 Protein, Human rHuFasR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; Fas1; Apo-1	Human	E. coli
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human has a full length of 157 amino acids (R17-N173), produced in E.coli with tag free.

HY-P76330

	Fas/CD95 Protein, Cynomolgus (HEK293) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Cynomolgus	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293) has a full length of 173 amino acids (M1-D173), produced in HEK293 cells with tag free.

HY-P7168

	Fas/CD95 Protein, Human (HEK293) rHuFasR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; Fas1; Apo-1	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.

HY-P73049

	Fas/CD95 Protein, Rat (HEK293, His) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Rat	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Rat Fas receptor contain a death domain (219-303 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Rat (HEK293, His) has a full length of 149 amino acids (Q22-K170), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P73047

	Fas/CD95 Protein, Human (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, Fc) has a full length of 173 amino acids (M1-N173), produced in HEK293 cells with C-terminal hFc-tag.

HY-P73048

	Fas/CD95 Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Rat	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Rat Fas receptor contain a death domain (219-303 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Rat (HEK293, Fc) produced in HEK293 cells with C-terminal hFc tag.

HY-P76331

	Fas/CD95 Protein, Cynomolgus (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Cynomolgus	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293, Fc) is produced in HEK293 cells with C-terminal hFc-tag.

HY-P70330

	Fas/CD95 Protein, Mouse (HEK293, His) rMuTumor necrosis factor receptor superfamily member 6//TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen Fas; FasLG receptor; CD95; Fas; TNFRSF6	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, His) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P700520

	Fas Ligand Protein, Human (His) 1 Publications Verification Apoptosis antigen ligand ; APTLCD95 ligand ; CD95-LFas antigen ligand ; Fas ligand ; FasL; CD178	Human	E. coli
	FASLG protein binds to TNFRSF6/FAS and triggers apoptotic signals.Fas Ligand Protein, Human (His) is the recombinant human-derived FASLG protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700521

	Fas Ligand Protein, Human (P.pastoris, His) Apoptosis antigen ligand ; APTLCD95 ligand ; CD95-LFas antigen ligand ; Fas ligand ; FasL; CD178	Human	P. pastoris
	FASLG protein binds to TNFRSF6/FAS and triggers apoptotic signals. Fas Ligand Protein, Human (P.pastoris, His) is the recombinant human-derived FASLG protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P700052AF

	Animal-Free Fas Ligand Protein, Human (His) 1 Publications Verification soluble Fas Ligand (sFasL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178	Human	E. coli
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Animal-Free Fas Ligand Protein, Human (His) has a total length of 152 amino acids (Q130-L281), is expressed in E. coli with N-terminal His-tag.This product is for cell culture use only.

HY-P700176AF

	Animal-Free Fas Ligand Protein, Mouse (His) 1 Publications Verification soluble Fas Ligand (sFasL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178; Fas-Lg; Tnfs; Tnlg1a; gld	Mouse	E. coli
	The cytoplasmic form of Fas ligand protein exerts powerful effects by inhibiting gene transcription. This protein plays a crucial role in regulating cellular processes by inhibiting the expression of specific genes. Animal-Free Fas Ligand Protein, Mouse (His) is the recombinant mouse-derived animal-FreeFas Ligand protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P74157

	Fas Ligand Protein, Mouse (P.pastoris, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Mouse	P. pastoris
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Mouse Fas Ligand has a total length of 279 amino acids (M1-L279), with a TNF_2 domain (144-279 a.a.). Fas Ligand Protein, Mouse (P.pastoris, His) is a recombinant protein expressed in P.pastoris cells with N-terminal His-tag.

HY-P72658

	Fas Ligand Protein, Human (HEK293, His, solution) 1 Publications Verification Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Human	HEK293
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (HEK293, His, solution) has a total length of 148 amino acids (P134-L281), is expressed in HEK392 cells with N-terminal 6*His-tag.

HY-P72658A

	Fas Ligand Protein, Human (HEK293, N-His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Human	HEK293
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (HEK293, His) has a total length of 148 amino acids (P134-L281), is expressed in HEK392 cells with N-terminal 6*His-tag.

HY-P74158

	Fas Ligand Protein, Human (148a.a, P.pastoris, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; Fas ligand; FasL; CD178; TNFSF6	Human	P. pastoris
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (148a.a, P.pastoris, His) has a total length of 148 amino acids (P134-L281), with a TNF_2 domain (146-281 a.a.). It is a recombinant protein expressed in P.pastoris cells with N-terminal His-tag.

HY-P70329

	Fas/CD95 Protein, Human (HEK293, His) rHuTumor necrosis factor receptor superfamily member 6/TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen Fas; FasLG receptor; APT1; Fas1; TNFRSF6 and Fas	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, His) has a full length of 147 amino acids (Q26-N173), produced in HEK293 cells with C-terminal 6*His-tag.

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Host:	Mouse (3) Rabbit (3)
Reactivity:	Human (6)
Application:	IHC-P (3) ICC/IF (5) IP (1) IHC-F (2) WB (4) FC (2) ELISA (3)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80666

	Fas Antibody (YA447) Fas; ALPS1A; APO-1; APT1; CD95; Fas1; FasTM; TNFRSF6	WB, IHC-F, IHC-P, ICC/IF	Human
	Fas Antibody (YA447) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P80666A

	Fas Antibody (YA447)(PBS only) Fas; ALPS1A; APO-1; APT1; CD95; Fas1; FasTM; TNFRSF6	WB, IHC-F, IHC-P, ICC/IF	Human
	Fas Antibody (YA447) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P85515

	Fas(C-term) Antibody (YA5207) ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen Fas; Apoptosis-mediating surface antigen Fas; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas; TNF receptor superfamily, member 6; Fas 1; Fas 827dupA; Fas AMA; Fas; Fas Antigen; Fas cell surface death receptor; Fas1; FasLG receptor; FasTM; sFas; Surface antigen APO1; TNF receptor superfamily, member 6; TNFRSF 6; TNFRSF6; TNR6_HUMAN; Tumor necrosis factor receptor superfamily member 6.	WB	Human
	Fas(C-term) Antibody (YA5207) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fas(C-term).

HY-P86549

	Fas Antibody (YA6241) Fas; APT1; Fas1; TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen Fas; FasLG receptor; CD antigen CD95	WB, IHC-P, ICC/IF, IP, ELISA	Human
	Fas Antibody (YA6241) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P84345

	Fas Ligand Antibody (YA4042) FasLG; APTL; FasL; CD95L; ALPS1B; CD95-L; TNFSF6; TNLG1A; APT1LG1; Fas Ligand Antibody	ICC/IF, FC, ELISA	Human
	Fas Ligand Antibody (YA4042) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fas Ligand.

HY-P84345A

	Fas Ligand Antibody (YA4042)(PBS only) FasLG; APTL; FasL; CD95L; ALPS1B; CD95-L; TNFSF6; TNLG1A; APT1LG1; Fas Ligand Antibody	ICC/IF, FC, ELISA	Human
	Fas Ligand Antibody (YA4042) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fas Ligand.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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