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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
GPI anchor
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "GPI anchor" in MCE Product Catalog:
3
Target:
Research Areas:
Synonyms: Vanin-1-IN-1
Target:
Research Areas:
PFI-653 (Vanin-1-IN-1, compound 3), a chemical probe, is a vanin-1 inhibitor that binds to plasma vanin-1 from mouse, rat, dog, and human. Vanin-1 is a cell surface-associated inositol (GPi) -anchored protein that plays important roles in metabolism and inflammation. PFI-653 inhibits vanin-1 from different species with IC50s of 6.85 nM (human recombinant plasma vanin-1), 9.0 nM (human plasma vanin-1), 24.5 nM (mouse recombinant vanin-1), and 53.4 nM (mouse plasma vanin-1) .
Cat. No.: HY-145316
CAS No.: 2054952-13-3
Target:
Research Areas:
Vanin-1-IN-2 is a potent vanin-1 inhibitor with an IC50 of 162 nM. Vanin-1 is a cell-surface-associated, glycosylphosphatidyl inositol (GPI)-anchored protein which is expressed at high levels in the kidney, liver, and small intestine .
Cat. No.: HY-131455A
Purity: ≥98.0%
Cat. No.: HY-165316
CAS No.: 13699-45-1
Target:
NOD-like Receptor (NLR) Interleukin Related Reactive Oxygen Species (ROS) Caspase TNF Receptor Apoptosis
Research Areas:
Myristoyllysophosphatidylcholine is a NLRP3 inflammasome inhibitor with multiple activities including anti-inflammatory and antioxidant effects. Myristoyllysophosphatidylcholine inhibits LPS-induced NLRP3 inflammasome activation, reduces pro-inflammatory cytokine secretion, decreases ROS and MDA levels, alleviates lung tissue and cell damage, and mediates apoptosis. Myristoyllysophosphatidylcholine serves as a myristate donor for myristoylation of the Glucose-6-Phosphate Isomerase (GPI) anchor in Trypanosoma brucei and undergoes hydrolysis. Myristoyllysophosphatidylcholine acts as a biomarker for the severity of community-acquired pneumonia. Myristoyllysophosphatidylcholine can be used in research related to diseases such as community-acquired pneumonia and acute lung injury .
Cat. No.: HY-P78033
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SEMA7A; CDw108; Prev. SEMAL; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, (Semaphorin) 7A; CD108; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, 7A; Semaphorin-7A; Semaphorin 7A (John Milton Hagen Blood Group); Sema
Cat. No.: HY-P78035A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SEMA7A; CDw108; Prev. SEMAL; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, (Semaphorin) 7A; CD108; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, 7A; Semaphorin-7A; Semaphorin 7A (John Milton Hagen Blood Group); Sema
Cat. No.: HY-182471
CAS No.: 1531626-08-0
Aminopyrifen is a GWT-1 inhibitor. Aminopyrifen inhibits the inositol acylation of phosphatidylinositol, disrupting the maturation process of GPI-anchored proteins and the integrity of fungal cell walls. Aminopyrifen strongly inhibits germ tube elongation of Botrytis cinerea, delays spore germination, prevents appressorium formation, and blocks the infection of plant tissues by pathogenic fungi. Aminopyrifen is effective against field populations of eggplant gray mold and cucumber powdery mildew, and can be used for research on various plant fungal diseases such as gray mold and powdery mildew .
Cat. No.: HY-P78035
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SEMA7A; CDw108; Prev. SEMAL; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, (Semaphorin) 7A; CD108; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, 7A; Semaphorin-7A; Semaphorin 7A (John Milton Hagen Blood Group); Sema
Cat. No.: HY-P705236
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA7A; CDw108; Prev. SEMAL; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, (Semaphorin) 7A; CD108; Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane anchor, 7A; Semaphorin-7A; Semaphorin 7A (John Milton Hagen Blood Group); Sema
Cat. No.: HY-P70384
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Cat. No.: HY-P76360
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Cat. No.: HY-P76948
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Cat. No.: HY-P76949
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Cat. No.: HY-P77371
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
