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Results for "

HARA

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

6

Natural
Products

3

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15871
    GGTI298 Trifluoroacetate
    5+ Cited Publications

    		 Apoptosis Cancer
    GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM.
    GGTI298 Trifluoroacetate
  • HY-100876
    GGTI298

    		Apoptosis Cancer
    GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
    GGTI298
  • HY-153488
    ISIS 2503

    		Ras Cancer
    ISIS-2503 is a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression
    ISIS 2503
  • HY-153488A
    ISIS 2503 sodium

    		Ras Cancer
    ISIS-2503 sodium is a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression
    ISIS 2503 sodium
  • HY-N9930
    Effusanin B

    		Fungal Infection
    Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity .
    Effusanin B
  • HY-N3950
    Glochidiol

    		Microtubule/Tubulin Cancer
    Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity .
    Glochidiol
  • HY-N19665
    (2S)-5,7,2',5'-Tetrahydroxyflavanone

    		Others Others
    (2S)-5,7,2',5'-Tetrahydroxyflavanone (Compound 6) is a flavanone that can be found in the roots of Scutellaria amabilis HARA. Flavanone possesses numerous biological activities, including antibacterial, anti-inflammatory, antitumor, and antioxidant effects .
    (2S)-5,7,2',5'-Tetrahydroxyflavanone
  • HY-N17920
    6α-Methoxygeniposide

    		Others Neurological Disease
    6α-Methoxygeniposide is a geniposide-type iridoid compound present in the leaves of Gardenia jasminoides cv. fortuneana HARA. 6α-Methoxygeniposide induces neurite outgrowth in pheochromocytoma cells .
    6α-Methoxygeniposide
  • HY-N1871
    4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol

    		Others Inflammation/Immunology
    4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol is a phenylethanoid isolated from the stem bark of Syringa reticulate (Bl.) Hara (Oleaceae) with expectorant and antiasthmatic activity .
    4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol
  • HY-180562
    KARS-IN-1

    		Ras Cancer
    KARS-IN-1 (152) is a AKR1C3 dependent KARS inhibitor with an AC50 of 9.1 nM for human KARS. KARS-IN-1 shows anti-proliferative activity in H460 (NRF2 pathway mutant cell line with high AKR1C3 expression) and Hara (NRF2 pathway wild type cell line with low AKR1C3 expression), with AC50 values ??of 21 nM and 16 nM, respectively. KARS-IN-1 can be used for the study of non-small cell lung cancer (NSCLC) .
    KARS-IN-1
  • HY-N16817
    Rabdoternin E

    		NO Synthase Inflammation/Immunology Cancer
    Rabdoternin E is a potential anti-inflammatory and antitumor agent. 2α-Acetoxy-14,15-cyclopimara-7β,16-diol only inhibits nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW264.7 macrophages (IC50=2.3 μM) and exhibits cytotoxicity against human tumor cells such as HL-60 and SW-480 (IC50 values ??of 2.6 μM and 4.1 μM, respectively). Rabdoternin E is an ent-kaurane-type diterpenoid compound that can be naturally extracted from the 70% acetone aqueous extract of the aerial parts of Isodon rosthornii (Diels) Hara (a plant of the Lamiaceae family, Isodon genus) .
    Rabdoternin E

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