8 Results for "

HBE

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "HBE" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-114544A
CAS No.: 168982-69-2
Purity:  ≥98.0%
Synonyms: OdDHL
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
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1
1 Cited Publications
Cat. No.: HY-13017S
CAS No.: 1413431-07-8
Purity:  99.83%
Synonyms: VX-770-d9
Ivacaftor-d9 is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research .
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Cat. No.: HY-123349
CAS No.: 13027-33-3
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease

5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM .
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Cat. No.: HY-169342
CAS No.: 2227484-71-9
Target:  

Sodium Channel

Research Areas:  

Inflammation/Immunology

ETD001 is a long-acting ENaC inhibitor, with an IC50 of 57.5 nM in cultured HBE cells. ETD001 can be used in the study for cystic fibrosis .
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Cat. No.: HY-RS06028
Research Areas:  

Others

HBE1 Human Pre-designed siRNA Set A contains three designed siRNAs for HBE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-13017S1
CAS No.: 1413431-22-7
Synonyms: VX-770-d19
Ivacaftor-d9 is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research .
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Cat. No.: HY-147742
CAS No.: 2307699-34-7
Target:  

JAK

Research Areas:  

Inflammation/Immunology

Thi-DPPY (compound 8e) is a potent and orally active JAK3 inhibitor with IC50 values of 62.4, 1.38 nM for BTK, JAK, respectively. Thi-DPPY shows anti-proliferative activity against HBE cells. Thi-DPPY shows anti-inflammatory activity in vivo. Thi-DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF) .
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Cat. No.: HY-157292
CAS No.: 3002962-69-5
Research Areas:  

Cancer

2E-3-F16 is a anticancer agent. 2E-3-F16 exhibits tumor cell selectivity between NCI-H446 cancer cells and HBE cells. 2E-3-F16 enhances the sensitivity of A549 cells to Cisplatin (HY-17394) .
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