5 Results for "

HCE cells

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "HCE cells" in MCE Product Catalog:

Nevadensin
Nevadensin
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Cat. No.: HY-N1377
CAS No.: 10176-66-6
Synonyms: Lysionotin
Category:  

other families Flavonoids Flavones Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Carboxylesterase (CES) Free Radical Scavengers DNA/RNA Synthesis Apoptosis Bacterial

Nevadensin (Lysionotin), a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities .
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Alisol G
Alisol G
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Cat. No.: HY-N0855
CAS No.: 155521-46-3
Synonyms: Alisol-G; 25-Anhydroalisol A
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

Carboxylesterase (CES) Bacterial HBV

Alisol G (25-Anhydroalisol A) is a human carboxylesterase 2 (hCES2) inhibitor with an IC50 of 3.85 μM. Alisol G exhibits cytotoxic activity against human cancer cells, antibacterial activity against Gram-positive strains, and anti-hepatitis B virus activity. Alisol G can be used in research related to lung cancer, breast cancer, prostate cancer, bacterial infections, and HBV infections .
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Benz-AP
Benz-AP
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Cat. No.: HY-147915
CAS No.: 2416220-53-4
Target:  

Carboxylesterase (CES) Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .
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Nevadensin (Standard)
Nevadensin (Standard)
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Cat. No.: HY-N1377R
CAS No.: 10176-66-6
Synonyms: Lysionotin (Standard)
Category:  

other families Flavonoids Flavones Phenols Polyphenols Plants

Target:  

Carboxylesterase (CES) Reference Standards DNA/RNA Synthesis Apoptosis Bacterial

Nevadensin (Standard) (Lysionotin (Standard)) is the analytical standard of Nevadensin (HY-N1377). This product is intended for research and analytical applications. Nevadensin, a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities.
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APD-209
APD-209
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Cat. No.: HY-182341
CAS No.: 1261156-82-4
Target:  

Drug Derivative

Research Areas:  

Infection

APD-209 is a sialic acid conjugate with a PEG4 polar linker and a PDA non-polar tail. APD-209 aggregates adenovirus type 37 particles, blocks the binding of viral particles to human corneal epithelial cells, and inhibits cellular entry of adenovirus type 37. APD-209 can be used for the research of epidemic keratoconjunctivitis .
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