155521-46-3
Chemical Structure
Alisol G
Synonym(s): Alisol-G; 25-Anhydroalisol A
- CAS 番号: 155521-46-3
- Formula:C30H48O4
- Molecular Weight:472.70
IUPAC Name: (5R,8S,9S,10S,11S,14R)-17-((2R,4S,5S)-4,5-dihydroxy-6-methylhept-6-en-2-yl)-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: WLNDANGOFVYODW-XCXJHVMUSA-N
SMILES: C[C@]([C@@]1(C2=C([C@H](C)C[C@H](O)[C@@H](O)C(C)=C)CC1)C)(CC[C@@]3([H])C4(C)C)[C@]([C@H](C2)O)([H])[C@]3(CCC4=O)C
Biological Activity: Alisol G (25-Anhydroalisol A) is a human carboxylesterase 2 (hCES2) inhibitor with an IC50 of 3.85 μM. Alisol G exhibits cytotoxic activity against human cancer cells, antibacterial activity against Gram-positive strains, and anti-hepatitis B virus activity. Alisol G can be used in research related to lung cancer, breast cancer, prostate cancer, bacterial infections, and HBV infections[1][2].
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Alisol G | 98.02% | Alisol G (25-Anhydroalisol A) is a human carboxylesterase 2 (hCES2) inhibitor with an IC50 of 3.85 μM. Alisol G exhibits cytotoxic activity against human cancer cells, antibacterial activity against Gram-positive strains, and anti-hepatitis B virus activity. Alisol G can be used in research related to lung cancer, breast cancer, prostate cancer, bacterial infections, and HBV infections. | ||||||||||||||||||||
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References
- [1]. Mai ZP, et al. Biotransformation of alisol G by Penicillium janthinellum and the hCE2 inhibitory effects of its metabolites. Phytochem Lett. 2015;13:228-233.
- [2]. Ma Q, et al. Structures and biological activities of the triterpenoids and sesquiterpenoids from Alisma orientale. Phytochemistry. 2016;131:150-157. [Content Brief]
