2416220-53-4
2416220-53-4
Chemical Structure
Benz-AP
- CAS No.: 2416220-53-4
- Formula:C20H13NO2
- Molecular Weight:299.32
IUPAC Name: N-(1-oxo-1H-phenalen-6-yl)benzamide
InChIKey: BNTPUIOPJAVWGQ-UHFFFAOYSA-N
SMILES: O=C(NC1=C2C=CC=C3C(C=CC(C=C1)=C32)=O)C4=CC=CC=C4
Biological Activity: Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids[1].
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Benz-AP | Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids. | |||||||||||||||||||||
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References
Keywords
