4 Results for "

HDAC-IN-7

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HDAC-IN-7" in MCE Product Catalog:

HDAC-IN-7
HDAC-IN-7
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Cat. No.: HY-13592
CAS No.: 743420-02-2
Synonyms: Chidamide impurity
Target:  

HDAC

Research Areas:  

Cancer

HDAC-IN-7 (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor.
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6
Apicidin
Apicidin
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6 Cited Publications
Cat. No.: HY-N6735
CAS No.: 183506-66-3
Synonyms: OSI 2040
Category:  

Infection Microorganisms Antibiotics Anti-parasitic Disease Research Anticancer Disease Research Fields Other Antibiotics

Target:  

HDAC Parasite

Apicidin (OSI 2040) is a fungal metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .
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4
7,4'-Dihydroxyflavone
7,4'-Dihydroxyflavone
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4 Cited Publications
Cat. No.: HY-N2609
CAS No.: 2196-14-7
Category:  

Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Endocrinology

Target:  

COX CCR NF-κB

7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
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7,4'-Dihydroxyflavone (Standard)
7,4'-Dihydroxyflavone (Standard)
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Cat. No.: HY-N2609R
CAS No.: 2196-14-7
Category:  

Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch.

Target:  

COX Reference Standards CCR NF-κB

7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
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