Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Hepa-1c1c7
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Hepa-1c1c7" in MCE Product Catalog:
2
Research Areas:
Omeprazole sulfide (Ufiprazole) is a metabolic degradation product of Omeprazole (HY-B0113). Omeprazole sulfide acts as a modulator of AhR. Omeprazole sulfide in cells with low CYP3A4 expression, functions as an AhR antagonist; however, in cells with high CYP3A4 expression, it is rapidly metabolized to Omeprazole, thereby acting as an AhR agonist. Omeprazole sulfide exhibits antibacterial activity when conjugated with silver nanoparticles (AgNPs). Omeprazole sulfide can be used in research on acid suppression and bacterial infections .
Synonyms: CGA-219417
Target:
Environmental Pollutants Aryl Hydrocarbon Receptor Androgen Receptor Fungal PERK Cytochrome P450
Research Areas:
Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .
Cat. No.: HY-N8268
CAS No.: 53608-86-9
Synonyms: 3α,12α-Dihydroxynorcholanic acid
Category:
Target:
Cat. No.: HY-N10344
CAS No.: 67920-64-3
Category:
Natural Products Camelina sativa (L.) Crantz Glucosinolates Plants Brassicaceae Disease Research Fields Cancer
Target:
Cat. No.: HY-147128
CAS No.: 2378039-23-5
Research Areas:
PY109 is an orally active and highly selective aryl hydrocarbon receptor (AHR) agonist. PY109's EC50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis .
Cat. No.: HY-N6802
CAS No.: 66069-55-4
Category:
Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer
Target:
Cat. No.: HY-167694
CAS No.: 856435-40-0
Target:
Research Areas:
Antiproliferative agent-62 (compound 5) is a functionalized benzylidene-indolin-2-one with notable antiproliferative activity and NQO1 activity induciton funciton, particularly in inducing NQO1 expression in murine Hepa1c1c7 cells and demonstrating effectiveness against human cancer cell lines, including MCF-7 and HCT116.
Cat. No.: HY-N8268R
CAS No.: 53608-86-9
Synonyms: 3α,12α-Dihydroxynorcholanic acid (Standard)
Category:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
