73590-85-9
Chemical Structure
Omeprazole sulfide
Synonym(s): Ufiprazole
- CAS No.: 73590-85-9
- Formula:C17H19N3O2S
- Molecular Weight:329.43
IUPAC Name: 6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
InChIKey: XURCIPRUUASYLR-UHFFFAOYSA-N
SMILES: CC(C(OC)=C(C)C=N1)=C1CSC2=NC3=CC=C(OC)C=C3N2
Biological Activity: Omeprazole sulfide (Ufiprazole) is a metabolic degradation product of Omeprazole (HY-B0113). Omeprazole sulfide acts as a modulator of AhR. Omeprazole sulfide in cells with low CYP3A4 expression, functions as an AhR antagonist; however, in cells with high CYP3A4 expression, it is rapidly metabolized to Omeprazole, thereby acting as an AhR agonist. Omeprazole sulfide exhibits antibacterial activity when conjugated with silver nanoparticles (AgNPs). Omeprazole sulfide can be used in research on acid suppression and bacterial infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Omeprazole sulfide | 99.88% | Omeprazole sulfide (Ufiprazole) is a metabolic degradation product of Omeprazole (HY-B0113). Omeprazole sulfide acts as a modulator of AhR. Omeprazole sulfide in cells with low CYP3A4 expression, functions as an AhR antagonist; however, in cells with high CYP3A4 expression, it is rapidly metabolized to Omeprazole, thereby acting as an AhR agonist. Omeprazole sulfide exhibits antibacterial activity when conjugated with silver nanoparticles (AgNPs). Omeprazole sulfide can be used in research on acid suppression and bacterial infections. | ||||||||||||||||||||
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Omeprazole sulfide (Standard) | ≥98% | Omeprazole sulfide (Standard) is the analytical standard of Omeprazole sulfide. This product is intended for research and analytical applications. Omeprazole sulfide is an Esomeprazole (HY-17021) precursor. Omeprazole sulfide can be converted to Esomeprazole by Lysinibacillus sp. B71. Esomeprazole can inhibit gastric H+/+ ATP enzyme. Omeprazole sulfide is mainly used in gastroesophageal reflux disease, gastric ulcer and antibacterial research. | ||||||||||||||||||||
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Omeprazole sulfide-d3 | 99.79% | Omeprazole sulfide-d3 is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor. | ||||||||||||||||||||
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- [1]. Gerbal-Chaloin S, et al. Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide. Cell Signal. 2006;18(5):740-750. [Content Brief]
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[2]. Ravanan A, et al. Study One-Pot Synthesis of Nanoparticles Omeprazole-Silver and Omeprazole Sulfide-Silver and Their Antibacterial Properties. Jundishapur Journal of Natural Pharmaceutical Products. 2025;20(20):e159909.
