53608-86-9
Chemical Structure
Nordeoxycholic acid
Synonym(s): 3α,12α-Dihydroxynorcholanic acid
- CAS. Nr.: 53608-86-9
- Formula:C23H38O4
- Molecular Weight:378.55
IUPAC Name: (R)-3-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)butanoic acid
InChIKey: PLRQOCVIINWCFA-AHFDLSHQSA-N
SMILES: C[C@@]1([C@@]2([H])[C@H](C)CC(O)=O)[C@](CC2)([H])[C@@](CC[C@@](C3)([H])[C@@]4(CC[C@H]3O)C)([H])[C@]4([H])C[C@@H]1O
Biological Activity: Nordeoxycholic acid (3α,12α-Dihydroxynorcholanic acid) is an orally active hydrophobic bile acid metabolite. Nordeoxycholic acid inhibits autophagic flux, induces endoplasmic reticulum stress and causes hepatocyte injury. Nordeoxycholic acid impairs intestinal barrier integrity in mice. Nordeoxycholic acid can be used in the research of alcohol-associated liver disease[1].
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Nordeoxycholic acid | 99.90% | Nordeoxycholic acid (3α,12α-Dihydroxynorcholanic acid) is an orally active hydrophobic bile acid metabolite. Nordeoxycholic acid inhibits autophagic flux, induces endoplasmic reticulum stress and causes hepatocyte injury. Nordeoxycholic acid impairs intestinal barrier integrity in mice. Nordeoxycholic acid can be used in the research of alcohol-associated liver disease. | ||||||||||||||||||||
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Nordeoxycholic acid (Standard) | ≥98% | Nordeoxycholic acid (3α,12α-Dihydroxynorcholanic acid) (Standard) is the analytical standard of Nordeoxycholic acid (HY-N8268). This product is intended for research and analytical applications. Nordeoxycholic acid is an orally active hydrophobic bile acid metabolite. Nordeoxycholic acid inhibits autophagic flux, induces endoplasmic reticulum stress and causes hepatocyte injury. Nordeoxycholic acid impairs intestinal barrier integrity in mice. Nordeoxycholic acid can be used in the research of alcohol-associated liver disease. | ||||||||||||||||||||
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Similarity Score 0.91
HY-43470R3α,12β-Dihydroxycholanoic acid (Standard) -
Similarity Score 0.91
HY-488143-Epideoxycholic acid -
Similarity Score 0.91
HY-N0593RDeoxycholic acid (Standard) -
Similarity Score 0.91
HY-N0593S3Deoxycholic acid-13C -
Similarity Score 0.91
HY-W725130Allodeoxycholic acid -
Similarity Score 0.87
HY-180625Bitocholate -
Similarity Score 0.86
HY-43466Methyl desoxycholate -
Similarity Score 0.85
HY-N0593ADeoxycholic acid sodium salt -
Similarity Score 0.85
HY-N158533α,12α-Dihydroxy-5β-cholestanoic acid -
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