Methyl desoxycholate
Based on 1 Customer Validation
Methyl desoxycholate is an ester product.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 3245-38-3
- Formula: C25H42O4
- Molecular Weight:406.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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HY-125731
Glycodeoxycholic acid
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HY-125801
3-Oxo-5β-cholanoic acid
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HY-76847
Chenodeoxycholic Acid
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HY-N0545
Taurocholic acid sodium
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HY-N0324
Cholic acid
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HY-76847R
Chenodeoxycholic Acid (Standard)
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HY-N0324R
Cholic acid (Standard)
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HY-N0545R
Taurocholic acid sodium (Standard)
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HY-107830
Methyl cholate
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HY-125801R
3-Oxo-5β-cholanoic acid (Standard)
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HY-107830R
Methyl cholate (Standard)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HET-1A | CC50 |
46 μM
Compound: 24, MeDCA
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Cytotoxicity against human HET-1A cells assessed as cell viability after 24 hrs by MTT assay
Cytotoxicity against human HET-1A cells assessed as cell viability after 24 hrs by MTT assay
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[PMID: 20713311] |
Chemical Information
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CAS No. 3245-38-3
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Appearance Solid
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Molecular Weight 406.60
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Formula C25H42O4
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Color White to off-white
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SMILES
O[C@@H]1CC[C@]2(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@@H]([C@H](C)CCC(OC)=O)CC[C@@]4([H])[C@]3([H])CC[C@@]([H])2C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (491.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4594 mL | 12.2971 mL | 24.5942 mL | 61.4855 mL |
| 5 mM | 0.4919 mL | 2.4594 mL | 4.9188 mL | 12.2971 mL | |
| 10 mM | 0.2459 mL | 1.2297 mL | 2.4594 mL | 6.1485 mL | |
| 15 mM | 0.1640 mL | 0.8198 mL | 1.6396 mL | 4.0990 mL | |
| 20 mM | 0.1230 mL | 0.6149 mL | 1.2297 mL | 3.0743 mL | |
| 25 mM | 0.0984 mL | 0.4919 mL | 0.9838 mL | 2.4594 mL | |
| 30 mM | 0.0820 mL | 0.4099 mL | 0.8198 mL | 2.0495 mL | |
| 40 mM | 0.0615 mL | 0.3074 mL | 0.6149 mL | 1.5371 mL | |
| 50 mM | 0.0492 mL | 0.2459 mL | 0.4919 mL | 1.2297 mL | |
| 60 mM | 0.0410 mL | 0.2050 mL | 0.4099 mL | 1.0248 mL | |
| 80 mM | 0.0307 mL | 0.1537 mL | 0.3074 mL | 0.7686 mL | |
| 100 mM | 0.0246 mL | 0.1230 mL | 0.2459 mL | 0.6149 mL |
Methyl desoxycholate Related Classifications
HY-43466 Related Classifications
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