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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Hypocholesterolemic
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Hypocholesterolemic" in MCE Product Catalog:
6
6 Cited Publications
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YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo . YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent . YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation .
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Synonyms: Agisterol
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LY 295427 is a LDL receptor modulator and a hypocholesterolemic agent. LY 295427 derepresses the transcription of the LDLR (LDL Receptor). LY 295427 can be used for hypercholesterolemia research .
Cat. No.: HY-169813
CAS No.: 81840-57-5
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Cat. No.: HY-100313
CAS No.: 182959-28-0
Category:
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Cat. No.: HY-120082
CAS No.: 179054-51-4
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FR-182980 is an orally active ACAT1 inhibitor (IC50: 30 nM). FR-182980 has hypocholesterolemic activity and can be used for research of atherosclerosis .
Cat. No.: HY-107959
CAS No.: 37296-80-3
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Colestipol hydrochloride, a hypocholesterolemic bile acid‐binding anion‐exchange polymer, is used in the study of hypercholesterolaemia .
Cat. No.: HY-Z8472
CAS No.: 77517-29-4
Synonyms: Lovastatin EP impurity E; 4a,5-Dihydromevinolin
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Cat. No.: HY-W015467
CAS No.: 636-73-7
Synonyms: Pyridine-3-sulphonic acid
Cat. No.: HY-P2424
CAS No.: 144396-38-3
Synonyms: CCK-J
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Cat. No.: HY-N5036
CAS No.: 109008-26-6
Synonyms: Ilexoside K
Category:
Cardiovascular Disease Aquifoliaceae Triterpenes Terpenoids Plants Disease Research Fields Tabernaemontana elegans Stapf
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Cat. No.: HY-117466
CAS No.: 179053-90-8
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FR186054 is an oral active acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with the IC50 of 99 nM. FR186054 shows hypocholesterolemic effect and can be used for study of hypercholesterolemia and atherosclerosis .
Cat. No.: HY-B1617AS
CAS No.: 2714316-71-7
Cat. No.: HY-P10872
Cat. No.: HY-P10906
CAS No.: 2868285-05-4
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Cat. No.: HY-P11455
Cat. No.: HY-19140
CAS No.: 124884-99-7
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YM17E hydrochloride is an acyl CoA:cholesterol acyltransferase (ACAT) inhibitor, with IC50 of 44 nM. YM17E hydrochloride has hypocholesterolemic effect .
Cat. No.: HY-P11766
Synonyms: GALA-cholesterol
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GALA-chol is a cholesterol-conjugated pH-responsive fusion peptide that can serve as a delivery adjuvant. GALA-chol enhances the endocytosis of siRNA RET/PTC1-SQ nanoparticles, inhibits cell viability, and undergoes pH-responsive charge conversion in the acidic lysosomal environment, thereby promoting lysosomal escape of small extracellular vesicle (sEV) cargo. GALA-chol anchors to the sEV membrane and maintains the structural integrity and intrinsic homing activity of sEVs. GALA-chol can be used in studies related to adjuvant delivery .
Cat. No.: HY-100313AR
CAS No.: 182959-33-7
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YM-53601 (Standard) is the analytical standard of YM-53601 (HY-100313A). This product is intended for research and analytical applications. YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo . YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent . YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
