81840-57-5
Chemical Structure
Yakuchinone B
- CAS No.: 81840-57-5
- Formula:C20H22O3
- Molecular Weight:310.39
InChIKey: OKVCTOBWIAGOMR-ACCUITESSA-N
SMILES: O=C(CCCCC1=CC=CC=C1)/C=C/C2=CC(OC)=C(C=C2)O
Biological Activity: Yakuchinone B is an Acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitor with hypocholesterolemic activity, which is found in the seeds of Zingiberaceae. Yakuchinone B inhibits rat hepatic ACAT with an IC50 value of 20.6 μM. Yakuchinone B is promising for research of hypercholesterolemia and atherosclerosis[1].
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Yakuchinone B | Yakuchinone B is an Acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitor with hypocholesterolemic activity, which is found in the seeds of Zingiberaceae. Yakuchinone B inhibits rat hepatic ACAT with an IC50 value of 20.6 μM. Yakuchinone B is promising for research of hypercholesterolemia and atherosclerosis. | |||||||||||||||||||||
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Keywords