8 Results for "

IgG1k

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "IgG1k" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99006
CAS No.: 931402-35-6
Synonyms: MORab-009

Target:  

Mesothelin

Research Areas:  

Cancer

Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium [1] .
loading...
    loading...
Cat. No.: HY-P99396
CAS No.: 2097104-58-8
Synonyms: BI 655130

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Spesolimab (BI 655130) is a mouse-derived humanized IgG1k antibody against IL-36R. IL-36 plays an important role in the immune system and Spesolimab is being investigated in palmoplantar pustulosis (PPP). Spesolimab was associated with a reduction in biomarkers associated with the innate, Th1/Th17 and neutrophil pathways [1] .
loading...
    loading...
Cat. No.: HY-P99995

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Human IgG1 (K214R) kappa, Isotype Control is a human IgG1 kappa monoclonal antibody mutant with a lysine-to-arginine substitution at position 214. Human IgG1 (K214R) kappa, Isotype Control is mainly used as an isotype control in experiments such as immunoprecipitation. Human IgG1 (K214R) kappa, Isotype Control binds to proteins non-specifically, thereby helping researchers verify the interactions of specific antibodies and ensure the accuracy of experimental results [1] .
loading...
    loading...
Cat. No.: HY-P99195
CAS No.: 1190239-42-9
Synonyms: REGN-475; SAR-164877

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies [1].
loading...
    loading...
Cat. No.: HY-P990077
CAS No.: 1036730-42-3
Synonyms: CT-011; MDV9300

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Pidilizumab (CT-011) is a humanized IgG1k anti-PD-1 monoclonal antibody. Pidilizumab acts as a DLL1 antagonist. Pidilizumab has the potential for hematologic malignancies research [1].
loading...
    loading...
Cat. No.: HY-P991120
CAS No.: 3010940-29-8
Synonyms: PF-08046040; SGN-CD70

Target:  

TNF Receptor

Research Areas:  

Cancer

Balertatug is a human IgG1K antibody targeting CD70. The corresponding isotype control is: Human lgG1 kappa, lsotype Control (HY-P99001) [1].
loading...
    loading...
Cat. No.: HY-P991119
CAS No.: 2866185-77-3

Target:  

Interleukin Related

Research Areas:  

Cancer

Balekafusp alfa is an IgG1K human antibody against IL-2 with anti-tumor activity. The corresponding isotype control is: Human lgG1 kappa, lsotype Control (HY-P99001) [1].
loading...
    loading...
Cat. No.: HY-P991131
CAS No.: 3011830-62-6

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Daretabart is a humanized IgG1K antibody targeting GD2, which can be used for anti-tumor research. The corresponding isotype control is: Human lgG1 kappa, lsotype Control (HY-P99001) [1].
loading...
    loading...