Human IgG1 (K214R) kappa, Isotype Control
Based on 1 Customer Validation
Human IgG1 (K214R) kappa, Isotype Control is a human IgG1 kappa monoclonal antibody mutant with a lysine-to-arginine substitution at position 214. Human IgG1 (K214R) kappa, Isotype Control is mainly used as an isotype control in experiments such as immunoprecipitation. Human IgG1 (K214R) kappa, Isotype Control binds to proteins non-specifically, thereby helping researchers verify the interactions of specific antibodies and ensure the accuracy of experimental results.
For research use only. We do not sell to patients.
- Purity: 96.41%
- Molecular Weight:142.74 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human IgG1 (K214R) kappa, Isotype Control does not inhibit NTHi-induced MyD88 K63-linked polyubiquitination, and induces NF-κB promoter activity to a degree similar to that of wild-type MyD88[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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Appearance Liquid
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Molecular Weight 142.74 kDa
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Color Colorless to light yellow
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SMILES
[Human IgG1 (K214R) kappa, Isotype Control]
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Chen L, et al. SIAH1-mediated RPS3 ubiquitination contributes to chemosensitivity in epithelial ovarian cancer. Aging (Albany NY). 2022;14(15):6202-6226. [Content Brief]
[2]. Lee BC, et al. Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88. Proc Natl Acad Sci U S A. 2016;113(2):E165-E171. [Content Brief]
[3]. Chen L, et al. Targeted destruction of VISTA boosts anti-tumor immunotherapy. Cell Res. 2025;35(12):987-1002. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Human IgG1 (K214R) kappa, Isotype Control Related Classifications
HY-P99995 Related Classifications
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