2. Inhibitory Antibodies
  3. Labetuzumab

Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy.

For research use only. We do not sell to patients.

Labetuzumab Chemical Structure

Labetuzumab Chemical Structure

CAS No. : 219649-07-7

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Labetuzumab Related Antibodies

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Description

Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy[1].

IC50 & Target

CEA[1].
In Vivo

Labetuzumab (0.5 mg/rat; i.v.; single) inhibits tumor growth in vivo[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female nu/nu mice (6 to 8-week-old; inject TT cells)[1].
Dosage: 0.5 mg/rat
Administration: Intravenous injection; single (1 day post-tumor cell injection)
Result: Significantly delaied growth of tumor, and led to 64%-70% inhibition of tumor size between days 32 and 60.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Labetuzumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.59%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Labetuzumab219649-07-7OthersMTCdacarbazinecancertumorthyroid cancerTT cellsInhibitorinhibitorinhibit

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