1 Result for "

LNSMGQD

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "LNSMGQD" in MCE Product Catalog:

LNSMGQD
LNSMGQD
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Cat. No.: HY-P11017
CAS No.: 1152066-26-6
Target:  

p38 MAPK Cadherin

Research Areas:  

Inflammation/Immunology

LNSMGQD is a cyclic peptide fragment derived from desmoglein 1 (amino acids 81-86), which mimics trans-interactions and acts as part of the tandem peptide binding interface of desmoglein 2. LNSMGQD not only binds to desmoglein 1 and 3, but also effectively inhibits their homophilic trans-interactions, while reducing the probability of homophilic or heterophilic binding between desmoglein 2 and Dsc2, N-cadherin and E-cadherin. LNSMGQD is applicable to the research on disease mechanisms such as Crohn's disease and pemphigus vulgaris .
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