MICAL2

By Targets:	Adenosine Receptor (1) Antibiotic (1) Apoptosis (1) Bacterial (1) Bombesin Receptor (2) Calcium Channel (1) DNA/RNA Synthesis (1) Endogenous Metabolite (4) Isotope-Labeled Compounds (4) NF-κB (1) PERK (2) Prostaglandin Receptor (1) Small Interfering RNA (siRNA) (1) Sodium Channel (1) Syk (2) Virus Protease (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Endocrinology (1) Infection (1) Inflammation/Immunology (5) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-109506S1

DPPC-d9 129Y83-d₉	Endogenous Metabolite	Others
DPPC-d₉ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-109506S

DPPC-d62 129Y83-d₆₂	Isotope-Labeled Compounds Endogenous Metabolite	Others
DPPC-d₆₂ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-131102

Mequindox	Bacterial DNA/RNA Synthesis	Infection
Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .

HY-RS08426

MICAL2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MICAL2 Human Pre-designed siRNA Set A contains three designed siRNAs for MICAL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MICAL2 Human Pre-designed siRNA Set A MICAL2 Human Pre-designed siRNA Set A

HY-109506S3

DPPC-d9-1 129Y83-d₉-1	Isotope-Labeled Compounds Endogenous Metabolite	Others
DPPC-d₉-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-101139

Xanthine amine congener XAC	Adenosine Receptor	Neurological Disease
Xanthine amine congener is a non-selective adenosine receptor antagonist . Xanthine amine congener induces convulsions in mice .

HY-P0107

RC-3095	Bombesin Receptor	Inflammation/Immunology
RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

HY-P0107A

RC-3095 TFA	Bombesin Receptor	Inflammation/Immunology
RC-3095 TFA is a selective bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

HY-D0195S

Acesulfame-d4 potassium	Isotope-Labeled Compounds	Others
Acesulfame-d₄ potassiumis the deuterium labeledAcesulfame (potassium)(HY-D0195) . Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice .

HY-103316A

Ned 19 2 Publications Verification	Calcium Channel	Cancer
Ned 19 is a selective membrane-permeant non competitive NAADP antagonist and inhibits NAADP-mediated Ca ²⁺ signaling, with an IC₅₀ of 65 nM . Ned 19 strongly inhibits tumor growth and vascularization as well as lung metastases in mice .

HY-133079

Ascorbyl tetra-2-hexyldecanoate tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate	Prostaglandin Receptor	Endocrinology
Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C (L-ascorbic acid). It protects against UVB-, hydrogen peroxide-, or tert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes when used at a concentration of 100 μM.1 Ascorbyl tetraisopalmitate (20 μM) decreases IL-1α and prostaglandin E2 production in unstimulated and UVB-stimulated HaCaT keratinocytes. Topical application of ascorbyl tetraisopalmitate (1%) increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice.2 Formulations containing ascorbyl tetraisopalmitate have been used in cosmetic products as skin-lightening agents.

HY-145119S

Mindeudesivir JT001 free base; VV116 free base; GS-621763-d₁	Isotope-Labeled Compounds	Others
GS-621763-d₁ is the deuterium labeled GS-621763 (HY-145119) . GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against *SARS-CoV-2* pathogenesis in mice .

HY-B0448S1

Phenytoin-15n2,13c	Sodium Channel Virus Protease
Phenytoin- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].

HY-12736

GSK143	Syk PERK	Inflammation/Immunology Cancer
GSK143 is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC₅₀ of 7.5. GSK143 inhibits phosphorylated Erk (pErk: pIC₅₀=7.1) . GSK143 reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice .

HY-12736A

GSK143 dihydrochloride	Syk PERK	Inflammation/Immunology Cancer
GSK143 dihydrochloride is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC₅₀ of 7.5. GSK143 dihydrochloride inhibits phosphorylated Erk (pErk: pIC₅₀=7.1) . GSK143 dihydrochloride reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice .

HY-107818

4-Hydroxychalcone	NF-κB	Cardiovascular Disease Inflammation/Immunology
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity . 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice .

HY-N1428S3

Citric acid-13C3	Apoptosis Endogenous Metabolite Antibiotic
Citric acid- ¹³C₃ is the ¹³C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

Cat. No.	Product Name	Target	Research Area

HY-P0107A

RC-3095 TFA	Bombesin Receptor	Inflammation/Immunology
RC-3095 TFA is a selective bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

HY-P0107

RC-3095	Bombesin Receptor	Inflammation/Immunology
RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107818

4-Hydroxychalcone	Cardiovascular Disease Flavonoids Chalcones Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	NF-κB
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity . 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice .

Cat. No.	Compare	Product Name	Species	Source

HY-P71756

	MICAL2 Protein, Human (P.pastoris, His) MICAL2; KIAA0750; MICAL2PV1; MICAL2PV2	Human	P. pastoris
	The MICAL2 protein is a methionine monooxygenase that crucially promotes F-actin depolymerization by oxidizing actin residues "Met-44" and "Met-47" to form methionine sulfoxide. This modification prevents actin filaments from repolymerizing. MICAL2 Protein, Human (P.pastoris, His) is the recombinant human-derived MICAL2 protein, expressed by P. pastoris , with N-His labeled tag. The total length of MICAL2 Protein, Human (P.pastoris, His) is 495 a.a., with molecular weight of ~58.5 kDa.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-109506S1

DPPC-d9
DPPC-d₉ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-109506S

DPPC-d62
DPPC-d₆₂ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-145119S

Mindeudesivir
GS-621763-d₁ is the deuterium labeled GS-621763 (HY-145119) . GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against *SARS-CoV-2* pathogenesis in mice .

HY-109506S3

DPPC-d9-1
DPPC-d₉-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-D0195S

Acesulfame-d4 potassium
Acesulfame-d₄ potassiumis the deuterium labeledAcesulfame (potassium)(HY-D0195) . Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice .

HY-B0448S1

Phenytoin-15n2,13c
Phenytoin- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].

HY-N1428S3

Citric acid-13C3
Citric acid- ¹³C₃ is the ¹³C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Name
Email *

	Sorry, but the email address you supplied was invalid.

MICAL2

Inhibitors & Agonists

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products