138147-78-1
Chemical Structure
RC-3095
- CAS No.: 138147-78-1
- Formula:C56H79N15O9
- Molecular Weight:1106.32
IUPAC Name: (S)-N1-((2S,5S,8S,14S,17S,20S)-14-((1H-imidazol-5-yl)methyl)-20-carbamoyl-1-(1H-indol-3-yl)-17-isobutyl-8-isopropyl-5,22-dimethyl-3,6,9,12,15-pentaoxo-4,7,10,13,16,19-hexaazatricosan-2-yl)-2-((R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamido)pen
InChIKey: IUYCRRDHLJIJBB-QAGBKCHLSA-N
SMILES: O=C([C@H]1CC(C(C=CC=C2)=C2N3)=C3CN1)N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@@H](CC(C)C)CN[C@H](C(N)=O)CC(C)C)=O)CC4=CN=CN4)=O)=O)=O)=O)CC5=CNC6=C5C=CC=C6)=O
Biological Activity: RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist[1]. RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RC-3095 | 99.43% | RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist. RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice. | ||||||||||||||||||||
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Similarity Score 0.95
HY-P0107ARC-3095 TFA -
Similarity Score 0.76
HY-103279BIM187 -
Similarity Score 0.74
HY-P4541(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) -
Similarity Score 0.73
HY-P11352JMV594 -
Similarity Score 0.73
HY-103281Litorin -
Similarity Score 0.69
HY-P1685Ranatensin -
Similarity Score 0.68
HY-P3835Mating Factor α (1-6) -
Similarity Score 0.67
HY-103283Neuromedin C (porcine) -
Similarity Score 0.67
HY-P5972GRP20–29, frog -
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References
- [1]. Roesler R, et al. RC-3095, a bombesin/gastrin-releasing peptide receptor antagonist, impairs aversive but not recognition memory in rats. Eur J Pharmacol. 2004 Feb 13;486(1):35-41. [Content Brief]
- [2]. Oliveira PG, et al. Protective effect of RC-3095, an antagonist of the gastrin-releasing peptide receptor, in experimental arthritis. Protective effect of RC-3095, an antagonist of the gastrin-releasing peptide receptor, in experimental arthritis. Arthritis Rheum. 2011 Oct;63(10):2956-65. [Content Brief]
