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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Myelotoxicity
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Myelotoxicity" in MCE Product Catalog:
AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range . AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation in vivo. AG-024322 induces cell apoptosis .
Synonyms: GBL-5g
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Research Areas:
UTL-5g (GBL-5g), an anti-inflammatory TNF-α inhibitor, has chemoprotective and liver radioprotective effects. UTL-5g lowers hepatotoxicity, nephrotoxicity, and myelotoxicity induced by Cisplatin through TNF-α inhibition among other factors .
Cat. No.: HY-154916
CAS No.: 139958-51-3
Synonyms: 13-DMT; 13-O-Demethyl FK 506
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Research Areas:
13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the major metabolite of Tacrolimus (HY-13756) formed via cytochrome P450 3A-mediated biotransformation. The ratio of 13-O-Desmethyl tacrolimus to Tacrolimus serves as a biomarker for myelotoxicity and hepatotoxicity .
Cat. No.: HY-129335
CAS No.: 54749-90-5
Synonyms: NSC 178248
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Chlorozotocin (NSC 178248) is a glucose-based chloroethylnitrosourea with low myelotoxicity for studying leukemia in mice .
Cat. No.: HY-16117A
CAS No.: 203258-38-2
Synonyms: PNU-166196
Target:
Research Areas:
Brostallicin (PNU-166196) is a DNA alkylating agent with potent cytotoxicity and low myelotoxicity .
Cat. No.: HY-115464
CAS No.: 150661-91-9
Target:
Research Areas:
NC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity .
Cat. No.: HY-W016183
CAS No.: 1806-29-7
Synonyms: o,o'-Biphenol
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
