9 Results for "

NK2R

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "NK2R" in MCE Product Catalog:

Cat. No.: HY-P10746
CAS No.: 2770688-48-5
Target:  

Neurokinin Receptor

Research Areas:  

Metabolic Disease

EB1002 is a highly selective, long-acting NK2R agonist. EB1002 exerts central appetite suppression, increases peripheral energy expenditure and enhances insulin sensitivity, which effectively reduces body weight, improves glucose and lipid metabolism, with favorable safety profiles. EB1002 can be used for research on diseases such as obesity and type 2 diabetes [2].
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Cat. No.: HY-P3849
CAS No.: 149270-28-0
Synonyms: LMN-NKA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), an analogue of Neurokinin A, is a selective and potent NK2R agonist. [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) has prokinetic activity. [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) can be used to study the roles of the NK-2 receptor in smooth muscle contraction in numerous tissues [2] .
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Cat. No.: HY-P0242
CAS No.: 86933-75-7
Neurokinin B is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B can be used in studies related to hypogonadotropic hypogonadism [2] .
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Cat. No.: HY-P0242A
CAS No.: 101536-55-4
Neurokinin B TFA is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B TFA preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B TFA regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B TFA exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B TFA can be used in studies related to hypogonadotropic hypogonadism [2] .
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Cat. No.: HY-117053
CAS No.: 169340-04-9
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [ 3H]NKA to native or cloned NK-2R from hamster bladder (Ki=2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [ 3H]NKA to cloned human NK-2R .
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Cat. No.: HY-122286
CAS No.: 272104-60-6
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

SB 414240 is a selective neurokinin-2 receptor (NK-2R) antagonist with Kis of 1 nM and 193 nM for human NK-3R and human NK-2R, respectively. SB 414240 does not bind the human μ-opioid receptor (hMOR). SB 414240 can be used for the study of neurological disease .
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Cat. No.: HY-P11075
CAS No.: 2770688-04-3
Target:  

Neurokinin Receptor

Research Areas:  

Metabolic Disease

[Lys5,Tyr6,mLeu9,Nle10]-Neurokinin A (4-10) (ID 305) is a selective NK2R agonist with an EC50 of 3.7  nM for hNK2R. [Lys5,Tyr6,mLeu9,Nle10]-Neurokinin A (4-10) significantly inhibits weight loss in diet-induced obese (DIO) mice model and improves Loperamide (HY-156131)-induced dysfunctional voiding in wild-type mice. [Lys5,Tyr6,mLeu9,Nle10]-Neurokinin A (4-10) can be used for neurokinin receptor mediated disorders, such as obesity, insulin resistance and type 2 diabetes research .
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Cat. No.: HY-RS14147
Research Areas:  

Others

Tacr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tacr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14146
Research Areas:  

Others

TACR2 Human Pre-designed siRNA Set A contains three designed siRNAs for TACR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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