272104-60-6
272104-60-6
Chemical Structure
SB 414240
- CAS No.: 272104-60-6
- Formula:C33H44N4O
- Molecular Weight:512.73
IUPAC Name: (S)-3-([1,4'-bipiperidin]-1'-ylmethyl)-N-(3,3-dimethylbutan-2-yl)-2-phenylquinoline-4-carboxamide
InChIKey: RTUNBOPBBCULLC-DEOSSOPVSA-N
SMILES: O=C(N[C@@H](C)C(C)(C)C)C1=C(C(C2=CC=CC=C2)=NC3=CC=CC=C13)CN4CCC(CC4)N5CCCCC5
Biological Activity: SB 414240 is a selective neurokinin-2 receptor (NK-2R) antagonist with Kis of 1 nM and 193 nM for human NK-3R and human NK-2R, respectively. SB 414240 does not bind the human μ-opioid receptor (hMOR). SB 414240 can be used for the study of neurological disease[1].
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SB 414240 | SB 414240 is a selective neurokinin-2 receptor (NK-2R) antagonist with Kis of 1 nM and 193 nM for human NK-3R and human NK-2R, respectively. SB 414240 does not bind the human μ-opioid receptor (hMOR). SB 414240 can be used for the study of neurological disease. | |||||||||||||||||||||
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