ZM 253270
ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [3H]NKA to native or cloned NK-2R from hamster bladder (Ki=2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [3H]NKA to cloned human NK-2R.
For research use only. We do not sell to patients.
- CAS No.: 169340-04-9
- Formula: C22H26ClN7O3
- Molecular Weight:471.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Hamster Bladder NK-2 2 nM (Ki) |
Chemical Information
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CAS No. 169340-04-9
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Molecular Weight 471.94
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Formula C22H26ClN7O3
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SMILES
O=C(N1CCN(CC1)C2=NC(C(N(C(C)C)C3)=O)=C3C(NC4=CC=C(C=C4)Cl)=N2)/C(C)=N/O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)