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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
NUDT1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "NUDT1" in MCE Product Catalog:
Target:
Research Areas:
BAY-707, a chemical probe, is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy [1].
Cat. No.: HY-RS09661
Target:
Research Areas:
NUDT1 Human Pre-designed siRNA Set A contains three designed siRNAs for NUDT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18535
Target:
Research Areas:
Nudt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nudt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25017
Target:
Research Areas:
Nudt1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nudt1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-187054
Research Areas:
NUDT1 ligand-1 is a NUDT1 ligand and can be used for the synthesis of PROTACs, such as LC-1-40 (HY-158062) [1].
Cat. No.: HY-158062
Target:
Research Areas:
LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM). LC-1-40 selectively inhibits MYCN-induced tumor growth in mouse models. LC-1-40 also induces nucleotide damage and apoptosis in MYCN-associated tumors. LC-1-40 can be used in cancer research [1]. (Red: NUDT1 binder; Blue: CRBN ligand; Black: Linker).
Cat. No.: HY-P74740
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NUDT1; Methylated Purine Nucleoside Triphosphate Hydrolase; Prev. MTH1; 8-Oxo-7,8-Dihydrodeoxyguanosine Triphosphatase; 7,8-Dihydro-8-Oxoguanine Triphosphatase; Nucleoside Diphosphate-Linked Moiety X Motif 1; Nudix Motif 1; 8-Oxo-7,8-Dihydroguanosine Trip
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
