2109805-96-9
2109805-96-9
Chemical Structure
BAY-707
- CAS No.: 2109805-96-9
- Formula:C15H20N4O2
- Molecular Weight:288.34
IUPAC Name: (S)-N-ethyl-4-(3-methylmorpholino)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
InChIKey: RPMGXDCRCWWCRY-JTQLQIEISA-N
SMILES: O=C(NCC)C(N1)=CC2=C1N=CC=C2N3CCOC[C@@H]3C
Biological Activity: BAY-707, a chemical probe, is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BAY-707 | 99.64% | BAY-707, a chemical probe, is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.93
HY-112081ABAY-707 acetate -
Similarity Score 0.55
HY-183451Y-30141 -
Similarity Score 0.55
HY-131263Hydroxychloroquine Impurity F -
Similarity Score 0.53
HY-10068Y-33075 hydrochloride -
Similarity Score 0.53
HY-10067Y-33075 -
Similarity Score 0.53
HY-W064918NITD-304 -
Similarity Score 0.53
HY-109588NITD-349 -
Similarity Score 0.53
HY-10069Y-33075 dihydrochloride -
Similarity Score 0.53
HY-177325MmpL3-IN-5 -
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