5 Results for "

Newman

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Newman" in MCE Product Catalog:

Cat. No.: HY-W141916
CAS No.: 7093-67-6
Synonyms: Tetraglycylglycine; Gly-Gly-Gly-Gly-Gly; NSC 96353
Research Areas:  

Infection

Pentaglycine (Tetraglycylglycine; NSC 96353) is a bridging structure composed of five glycine residues. Pentaglycine serves as a characteristic peptidoglycan cross-bridge component of staphylococci and a specific substrate for lysostaphin. Pentaglycine maintains the integrity of the peptidoglycan cell wall of Staphylococcus aureus via peptide chain cross-linking and regulates bacterial growth. Pentaglycine expression is downregulated in high-glucose environments, inhibiting bacterial proliferation. Pentaglycine can be applied to studies related to Staphylococcus aureus infection .
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Cat. No.: HY-115658
CAS No.: 38376-29-3
Purity:  99.62%
Target:  

Bacterial

Research Areas:  

Infection Metabolic Disease

VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus .
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Cat. No.: HY-115990
CAS No.: 2883403-42-5
Target:  

Topoisomerase Bacterial

Research Areas:  

Infection

Topoisomerase IV inhibitor 2 (compound 7d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.23 μM and 0.43 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 0.972 μM and 0.608 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively .
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Cat. No.: HY-N15550
CAS No.: 1206881-48-2
Category:  

Microorganisms Antibiotics

Target:  

Antibiotic Bacterial

Armeniaspirol B is a selective antibiotic targeting Gram-positive pathogens, showing MIC values of 0.5 μg/mL against S. aureus Newman and 2.0 μg/mL against S. aureus USA300. Armeniaspirol B is promising for research of Gram-positive bacterial infections (e.g., MRSA, VRE infections) .
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Cat. No.: HY-115991
CAS No.: 2883403-36-7
Target:  

Topoisomerase Bacterial

Research Areas:  

Infection

Topoisomerase IV inhibitor 2 (compound 5d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.35 μM and 0.55 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 1.985 μM and 0.744 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively .
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