28 Results for "

OX40 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "OX40 receptor" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P78189
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P99570
CAS No.: 2126777-87-3
Synonyms: GBR-830

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Telazorlimab (GBR-830) is a humanized monoclonal antibody against OX40 costimulatory receptor on activated T cells. Telazorlimab can be used for the research of autoimmune diseases .
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Cat. No.: HY-P99159
CAS No.: 2128729-41-7

Target:  

Interleukin Related

Research Areas:  

Cancer

Ivuxolimab is a fully human IgG2 agonist targeting OX40 (CD134), which selectively binds to the OX40 receptor on the surface of activated CD4 + and CD8 + T cells without inducing antibody-dependent cytotoxicity. Ivuxolimab can promote T cell proliferation, survival and cytokine (such as IFN-γ, IL-2) secretion, inhibit regulatory T cell function, and enhance anti-tumor immune response. Ivuxolimab can be used in the study of melanoma, hepatocellular carcinoma, head and neck squamous cell carcinoma, etc .
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Cat. No.: HY-P991336
CAS No.: 2708115-83-5
Synonyms: INBRX-106; ES-102
Ordastobart (INBRX-106; ES-102) is a hexavalent OX40 agonist antibody. Ordastobart enhances OX40 receptor clustering, signaling, and downstream activation, thereby increasing the proliferation and activation of CD4 + and CD8 + T cells in vitro and in vivo. Ordastobart exhibits anti-tumor effects and improves survival in mouse models of cancer. Ordastobart is indicated for research in cancers such as fibrosarcoma and colorectal cancer .
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Cat. No.: HY-103333
CAS No.: 128007-31-8
Purity:  ≥99.0%
Synonyms: N-Vanillylarachidonamide
Arvanil (N-Vanillylarachidonamide) is a mixed agonist of CB1 and TRPV1 receptors. Arvanil downregulates CD25, HLA-DR, CD134/OX40, blocks G1/S phase transition, and induces phosphorylation of Akt. Arvanil does not induce apoptosis in cells. Arvanil inhibits lymphocyte activation and ameliorates autoimmune encephalomyelitis. Arvanil can be used in research related to Huntington's disease, vomiting, and multiple sclerosis .
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Cat. No.: HY-P99945
CAS No.: 2230138-89-1
Synonyms: ABBV-368
Revdofilimab (ABBV-368) is a human IgG1 agonist monoclonal antibody against OX40. Among them, OX40 is a member of the TNF receptor superfamily expressed on activated and memory T cell subsets and T regulatory cells .
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Cat. No.: HY-P991338

Research Areas:  

Cancer

MEDI-6469 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134. MEDI-6469 targets the OX40 receptor on activated T cells to enhance the immune response against cancer cells. .
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Cat. No.: HY-151506
CAS No.: 2274812-94-9
Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity .
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Cat. No.: HY-P99911
CAS No.: 1635395-27-5
Synonyms: MEDI-6383
Efizonerimod alfa (MEDI-6383) is a recombinant human OX40L IgG4P Fc fusion protein that assembles into a hexameric structure and exerts potent agonist activity upon binding to OX40. The activity of Efizonerimod alfa is enhanced by Fcγ receptor-mediated aggregation. Efizonerimod alfa binds to OX40 on the surface of activated T cells, induces NF-κB promoter activity in OX40-expressing T cells, and triggers the production of Th1-type cytokines, T cell proliferation, and resistance to regulatory T cell (Treg)-mediated suppression. Efizonerimod alfa enhances the cytolytic activity of tumor-reactive T cells and slows tumor growth in immunodeficient mice. Efizonerimod alfa induces the proliferation of CD4, CD8, and B cells in the peripheral blood of healthy non-human primates. Efizonerimod alfa can be used in the research of advanced solid malignancies and melanoma .
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Cat. No.: HY-P991529

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

AGEN-2373 is a conditionally active agonist antibody targeting the co-stimulatory receptor CD137. GEN-2373 binds to CD137 without disruption of ligand binding. AGEN-2373 stimulates CD137 under receptor clustering conditions. AGEN-2373 can enhance T cell activity when combined with other checkpoint modulators (e.g. PD-1 antagonist and OX40 agonist). AGEN-2373 can be studied in research for human malignancies .
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Cat. No.: HY-P7394
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P70813
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P72499
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P78334
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P78188
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P78503
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P704275
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P70549
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P75954
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Cat. No.: HY-P72404
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor receptor Superfamily, Member 4; Tumor Necrosis Factor receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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