Orcinol

By Targets:	Endogenous Metabolite (1) ERK (1) Fluorescent Dye (1) Keap1-Nrf2 (1) mTOR (1) p38 MAPK (2) Reference Standards (1) TGF-β Receptor (1) Tyrosinase (2) Wnt (2)
By Research Areas:	Cancer (1) Metabolic Disease (2) Neurological Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0168

*Orcinol* 3,5-Dihydroxytoluene	Fluorescent Dye Tyrosinase p38 MAPK ERK	Metabolic Disease Cancer
Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

HY-N0008

Orcinol glucoside	Wnt p38 MAPK mTOR Keap1-Nrf2 TGF-β Receptor	Neurological Disease Metabolic Disease
Orcinol glucoside is an orally active, blood-brain barrier permeable osteoblast proliferation promoter that targets the Nrf2/Keap1, mTOR and p38 signaling pathways. Orcinol glucoside promotes Nrf2 nuclear translocation, upregulates antioxidant enzyme levels, enhances the phosphorylation of mTOR and p70S6K, and inhibits the enzymatic activity of HAS2 as well as the nuclear translocation of GR. Orcinol glucoside also alleviates oxidative stress, inhibits autophagic flux, osteoclastogenesis and TGF-β1-induced M2 polarization, while reducing collagen deposition and effectively promoting the proliferation, differentiation and mineralization of osteoblasts. Orcinol glucoside also exhibits anti-pulmonary fibrosis, anxiolytic and antidepressant activities. Orcinol glucoside can be used in the research of senile and glucocorticoid-induced osteoporosis, idiopathic pulmonary fibrosis (IPF), anxiety and other related diseases .

HY-W015715

5-Methylresorcinol monohydrate Orcinol monohydrate	Tyrosinase	Neurological Disease
5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. 5-Methylresorcinol monohydrate shows cytotoxicity. 5-Methylresorcinol monohydrate also is an oral active and cross the blood-brain barrier anxiolytic agent .

HY-N4123

Orcinol gentiobioside 1 Publications Verification	Others	Others
Orcinol gentiobioside (compound 4) is a natural product isolated from the rhizomes of C. breviscapa .

HY-N0008R

Orcinol glucoside (Standard)	Reference Standards Wnt	Neurological Disease
Orcinol glucoside (Standard) is the analytical standard of Orcinol glucoside. This product is intended for research and analytical applications. Orcinol glucoside (OG) is an active constituent isolated from Curculigo orchioides, with antidepressant effects. Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signaling pathway .

HY-W727144

2-Heptyl-4,6-dihydroxybenzoic acid	Endogenous Metabolite	Others
2-Heptyl-4,6-dihydroxybenzoic acid (compound 6b) is a known component of orcinol .

HY-N13329

Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside	Others	Others
Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside is a natural product .

Cat. No.	Product Name	Type

HY-D0168

*Orcinol* 3,5-Dihydroxytoluene	Fluorescent Dyes
Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

Orcinol

3,5-Dihydroxytoluene

Fluorescent Dyes

Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

Cat. No.	Product Name	Type

HY-W015715

5-Methylresorcinol monohydrate Orcinol monohydrate	Biochemical Assay Reagents
5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. 5-Methylresorcinol monohydrate shows cytotoxicity. 5-Methylresorcinol monohydrate also is an oral active and cross the blood-brain barrier anxiolytic agent .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0168

*Orcinol* 3,5-Dihydroxytoluene	Microorganisms Classification of Application Fields Other Diseases Phenols Polyphenols Ericaceae Plants Disease Research Fields Source Classification	Fluorescent Dye Tyrosinase p38 MAPK ERK
Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

HY-N0008

Orcinol glucoside	Curculigo orchioides Gaertn. Structural Classification Monophenols Phenols Plants Amaryllidaceae Source Classification	Wnt p38 MAPK mTOR Keap1-Nrf2 TGF-β Receptor
Orcinol glucoside is an orally active, blood-brain barrier permeable osteoblast proliferation promoter that targets the Nrf2/Keap1, mTOR and p38 signaling pathways. Orcinol glucoside promotes Nrf2 nuclear translocation, upregulates antioxidant enzyme levels, enhances the phosphorylation of mTOR and p70S6K, and inhibits the enzymatic activity of HAS2 as well as the nuclear translocation of GR. Orcinol glucoside also alleviates oxidative stress, inhibits autophagic flux, osteoclastogenesis and TGF-β1-induced M2 polarization, while reducing collagen deposition and effectively promoting the proliferation, differentiation and mineralization of osteoblasts. Orcinol glucoside also exhibits anti-pulmonary fibrosis, anxiolytic and antidepressant activities. Orcinol glucoside can be used in the research of senile and glucocorticoid-induced osteoporosis, idiopathic pulmonary fibrosis (IPF), anxiety and other related diseases .

HY-N4123

Orcinol gentiobioside 1 Publications Verification	Curculigo orchioides Gaertn. Monophenols Classification of Application Fields Other Diseases Phenols Plants Disease Research Fields Amaryllidaceae Source Classification	Others
Orcinol gentiobioside (compound 4) is a natural product isolated from the rhizomes of C. breviscapa .

HY-N0008R

Orcinol glucoside (Standard)	Curculigo orchioides Gaertn. Structural Classification Monophenols Phenols Plants Amaryllidaceae Source Classification	Reference Standards Wnt
Orcinol glucoside (Standard) is the analytical standard of Orcinol glucoside. This product is intended for research and analytical applications. Orcinol glucoside (OG) is an active constituent isolated from Curculigo orchioides, with antidepressant effects. Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signaling pathway .

HY-N13329

Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside	Hypoxidaceae Phenols Plants Source Classification	Others
Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside is a natural product .

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Orcinol

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

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