1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. 5-Methylresorcinol monohydrate

5-Methylresorcinol monohydrate  (Synonyms: Orcinol monohydrate)

Cat. No.: HY-W015715
Handling Instructions

5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. 5-Methylresorcinol monohydrate shows cytotoxicity. 5-Methylresorcinol monohydrate also is an oral active and cross the blood-brain barrier anxiolytic agent.

For research use only. We do not sell to patients.

5-Methylresorcinol monohydrate Chemical Structure

5-Methylresorcinol monohydrate Chemical Structure

CAS No. : 6153-39-5

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Based on 1 publication(s) in Google Scholar

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Description

5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. 5-Methylresorcinol monohydrate shows cytotoxicity. 5-Methylresorcinol monohydrate also is an oral active and cross the blood-brain barrier anxiolytic agent[1][2].

In Vitro

5-Methylresorcinol monohydrate (Orcinol monohydrate) (100, 200, 500 µM; 24, 72 h) shows cytotoxicity for B16, Hs68 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: B16, Hs68 cells
Concentration: 100, 200, 500 µM
Incubation Time: 24, 72 h
Result: Showed cytotoxicity with the inhibition rate of 101.7% for Hs68 cells at 24 h and 104.4% inhibition rate for B16 cells at 72 h.
In Vivo

5-Methylresorcinol monohydrate (2.5, 5 mg/kg; p.o.) shows anxiolytic activity without sedative effects [2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 18-22 g Male CD-1 mice[2]
Dosage: 2.5, 5 mg/kg
Administration: P.o.
Result: Increased the time spent in open arms and the number of entries into open arms in the elevated plus-maze test, increased the number of head-dips in the hole-board test; did not significantly affect the locomotion of mice in the open-field test.
Molecular Weight

142.15

Formula

C7H10O3

CAS No.
Unlabeled CAS

Appearance

Solid

SMILES

OC1=CC(C)=CC(O)=C1.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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5-Methylresorcinol monohydrate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
5-Methylresorcinol monohydrate
Cat. No.:
HY-W015715
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