Search Result
Results for "
PEG5 linker
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-141269
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-101157
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-126885
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ADC Linker
PROTAC Linkers
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Cancer
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DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-120702
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ADC Linker
PROTAC Linkers
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Cancer
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N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130388
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-126889
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-120537
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W190962
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PROTAC Linkers
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Cancer
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BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141214
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PROTAC Linkers
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Cancer
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W022240
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PROTAC linker 17
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PROTAC Linkers
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Cancer
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NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-130271
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VH032-PEG5-COOH; VHL Ligand-linker Conjugates 16; E3 Ligase Ligand-linker Conjugates 58
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology .
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- HY-126976
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-112495
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HaloPROTAC 2
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
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- HY-W040195
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PROTAC Linkers
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Cancer
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m-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-116006
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PROTAC linker 36
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PROTAC Linkers
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Cancer
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Bis-PEG5-acid (PROTAC Linker 36) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. Bis-PEG5-acid (PROTAC Linker 36) can be used in the synthesis of the CP5V. CP5V is a PROTAC, and specifically degrades Cdc20 .
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- HY-131647
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Pomalidomide-PEG5-CO2H
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology .
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- HY-115384
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-134682
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PROTAC Linkers
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Cancer
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Fmoc-NH-PEG5-C2-NH2 is a PEG-based PROTAC linker. Fmoc-NH-PEG5-C2-NH2 can be used in the synthesis of PROTACs .
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- HY-140008
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PROTAC Linkers
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Cancer
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DOTA-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140743
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141366
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PROTAC Linkers
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Cancer
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Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-23417
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PROTAC Linkers
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Cancer
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PEG5-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-145736A
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Drug-Linker Conjugates for ADC
Apoptosis
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Cancer
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β-Glucuronide-dPBD-PEG5-NH2 TFA is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD.β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2 TFA, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 TFA can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 TFA has antitumor activity .
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- HY-140267
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PROTAC Linkers
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Cancer
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DBCO-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-129637
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PROTAC Linkers
ADC Linker
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Cancer
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NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W552310
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- HY-133062
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ADC Linker
PROTAC Linkers
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Cancer
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Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-129622
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PROTAC Linkers
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Cancer
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NH2-PEG5-C6-Cl (K-7) is a linker which refers to the PEG composition. NH2-PEG5-C6-Cl can be used in the synthesis of a series of compounds that induce degradation of intracellular molecules by autophagy .
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- HY-145736
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Drug-Linker Conjugates for ADC
Apoptosis
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Cancer
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β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 has antitumor activity .
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- HY-141275
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-122459
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PROTAC Linkers
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Cancer
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Fmoc-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141408
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PROTAC Linkers
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Cancer
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m-PEG5-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-130601
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- HY-120845
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- HY-133193
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PROTAC Linkers
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Infection
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Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity . Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130150
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PROTAC Linkers
ADC Linker
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Inflammation/Immunology
Cancer
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m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-succinimidyl carbonate is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W1130361
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Ligands for E3 Ligase
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Cancer
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(S,R,S)-AHPC-PEG5-Azide is a VHL ligand based on (S,R,S)-AHPC that recruits von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-PEG5-Azide can be linked to a target protein ligand via a linker to form a PROTACs.
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- HY-W998297
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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(S,R,S)-AHPC-CO-C-PEG5-amine hydrochloride is an E3 ligase ligand-linker conjugate containing a VHL ligand and linker based on (S,R,S)-AHPC. (S,R,S)-AHPC-CO-C-PEG5-amine hydrochloride can be used to synthesize PROTAC.
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- HY-133006
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PROTAC Linkers
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Cancer
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Fluorescein-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-140483
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PROTAC Linkers
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Cancer
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Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W042714
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PROTAC Linkers
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Cancer
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BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-133065
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PROTAC Linkers
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Cancer
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m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W042501
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PROTAC Linkers
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Cancer
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m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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- HY-126917
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PROTAC Linkers
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Cancer
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133272
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PROTAC Linkers
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Cancer
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m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141375
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PROTAC Linkers
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Cancer
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m-PEG5-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141082
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PROTAC Linkers
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Cancer
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Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133293
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HS-PEG5-OH
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PROTAC Linkers
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Cancer
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Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141095
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PROTAC Linkers
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Cancer
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Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-116186
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG5-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-139333
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC .
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- HY-141296
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PROTAC Linkers
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Cancer
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PEG5-bis-(Ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-159777
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- HY-138403
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PROTAC Linkers
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Cancer
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THP-C1-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138529
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PROTAC Linkers
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Cancer
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Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138528
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PROTAC Linkers
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Cancer
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Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141055
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PROTAC Linkers
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Cancer
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Cy5-PEG5-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126962
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PROTAC Linkers
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Cancer
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Mal-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-138487
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133051
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PROTAC Linkers
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Cancer
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Hydroxy-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W108220
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W096131
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PROTAC Linkers
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Cancer
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Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140549
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PROTAC Linkers
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Cancer
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NH-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130657
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PROTAC Linkers
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Cancer
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m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-133384
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PROTAC Linkers
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Cancer
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SPDP-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133290
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HS-PEG5-CH2CH2COOH
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PROTAC Linkers
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Cancer
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Thiol-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130895
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PROTAC Linkers
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Cancer
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Bis-Mal-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096160
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PROTAC Linkers
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Cancer
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Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096161
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PROTAC Linkers
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Cancer
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Bis-methacrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132070
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Folic acid-PEG5-Mal
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PROTAC Linkers
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Cancer
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FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140965
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PROTAC Linkers
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Cancer
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Mal-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140754
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PROTAC Linkers
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Cancer
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Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133210
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PROTAC Linkers
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Cancer
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Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096075
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096157
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PROTAC Linkers
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Cancer
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140751
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138385
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PROTAC Linkers
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Cancer
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MS-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141298
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PROTAC Linkers
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Cancer
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Bromo-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140175
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PROTAC Linkers
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Cancer
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Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140749
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PROTAC Linkers
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Cancer
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BnO-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138378
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141308
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PROTAC Linkers
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Cancer
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m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135921
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PROTAC Linkers
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Cancer
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m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-143832
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PROTAC Linkers
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Cancer
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Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141283
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096105
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PROTAC Linkers
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Cancer
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Nonylbenzene-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138728
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PROTAC Linkers
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Cancer
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Mal-amido-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141094
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PROTAC Linkers
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Cancer
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Pyrene-PEG5-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-140169
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxy-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138373
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG5-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140171
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141093
-
|
|
PROTAC Linkers
|
Cancer
|
|
Pyrene-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133352
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W592008
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C18-PEG5-Acid is a hybrid linker featuring a hydrophobic C18 chain and hydrophilic PEG5 spacer with a carboxylic acid. The carboxylic acid is reactive with amines to form a stable amide bond.
|
-
- HY-101157R
-
|
|
ADC Linker
Reference Standards
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-acid (Standard) is the analytical standard of Propargyl-PEG5-acid (HY-101157). This product is intended for research and analytical applications. Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W1130398
-
-
- HY-W594797
-
-
- HY-W190936
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-O-PEG5-Tosyl is a molecule that incorporatess the Thalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. Thalidomide-O-PEG5-tosyl is reactive with nucleophiles such as amine, hydroxy containing molecules.
|
-
- HY-134682A
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker. Fmoc-NH-PEG5-C2-NH2 hydrochloride can be used in the synthesis of PROTACs .
|
-
- HY-W1130362
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG5-GGG-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-138330
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126999
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040245
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-amino-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141396
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141374
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140194
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140512
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-TEMPO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130523
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130147
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156490
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-130330
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140302
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140958
-
|
|
PROTAC Linkers
|
Cancer
|
|
DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-132043
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140046
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138719
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138736
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141301
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141191
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130447
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-amine is a PEG-based (5 units) PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140935
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141276
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140384
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140485
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140428
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138732
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134709
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141305
-
|
|
PROTAC Linkers
|
Cancer
|
|
Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141312
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140553
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134738
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetamide-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140629
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138748
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126888
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-135938
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129622A
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129621
-
|
|
PROTAC Linkers
|
Cancer
|
|
N3-PEG5-C6-Cl is a PEG PROTAC linker, can be used for synthesis of HALo PROTAC .
|
-
- HY-133475
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133467
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG5-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140053
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-148662
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-136140
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140880
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140275
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-134688
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetamide-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140896
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140251
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141406
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-134681
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2420
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-Mal is a PROTAC linker, belonging to the PEG class. It can be used for the synthesis of PROTAC molecules .
|
-
- HY-140225
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140392
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130551
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-171559
-
|
|
PROTAC Linkers
|
Others
|
|
TCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG5-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups .
|
-
- HY-130211
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130489
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140810
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-(Azido-PEG5-amino)propanol is a PEG linker which contains an azide moiety and a hydroxyl group. 3-(Azido-PEG5-amino)propanol is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.
|
-
- HY-156170
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-5-NH-PEG5-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-NH-PEG5-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
|
-
- HY-133463
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-Ph-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133070
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140481
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133544
-
|
|
ADC Linker
|
Cancer
|
|
Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-144080
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140489
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141243
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140366
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134750
-
|
|
PROTAC Linkers
|
Cancer
|
|
HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134678
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propanol-PEG5-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130577
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133340
-
|
|
PROTAC Linkers
|
Cancer
|
|
H2N-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141210
-
|
Hydroxy-PEG5-t-butyl acetate
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190931
-
-
- HY-138773
-
-
- HY-130572
-
|
|
PROTAC Linkers
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134679
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-C1-PEG5-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140314
-
|
|
PROTAC Linkers
|
Cancer
|
|
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130945
-
|
|
ADC Linker
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Cancer
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Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-125541
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ADC Linker
PROTAC Linkers
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Cancer
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DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-126381
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PROTAC Linkers
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Cancer
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Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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-
- HY-135919
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PROTAC Linkers
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Cancer
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Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-141059
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PROTAC Linkers
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Cancer
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Cy5-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Cy5-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140537
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PROTAC Linkers
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Cancer
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N-(Boc-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-138375
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PROTAC Linkers
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Cancer
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|
Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-138784
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-
- HY-138784A
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-
- HY-W096140
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PROTAC Linkers
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Cancer
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Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-133816A
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-amino-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .
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-
- HY-133816
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .
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-
- HY-136054
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ADC Linker
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Cancer
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|
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140753
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PROTAC Linkers
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Cancer
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|
DOTA-(t-butyl)3-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-(t-butyl)3-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-163549
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-
- HY-W096092
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PROTAC Linkers
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Cancer
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|
BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-141037
-
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PROTAC Linkers
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Cancer
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|
N-(m-PEG9)-N'-(PEG5-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-W043840
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|
PROTAC Linkers
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Cancer
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|
m-PEG5-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
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-
- HY-164785
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Drug Intermediate
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Others
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|
TCO-PEG5-maleimide is a PEG linker with TCO and maleimide groups, specifically enabling tetrazine click chemistry and thiol conjugation for bioconjugation, probe design, and drug delivery.
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-
- HY-W999557
-
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|
E3 Ligase Ligand-Linker Conjugates
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Cancer
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|
(R,S,S)-VH032-PEG5-N3 is an E3 ligase ligand-linker conjugate comprising a VHL ligand based on VH032 and a 5-unit PEG linker. (R,S,S)-VH032-PEG5-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azido-azynylene cycloaddition (CuAAc) with molecules containing an alkyne group. It can also undergo ring-strain-driven alkyne-azido cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-140752
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|
PROTAC Linkers
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Cancer
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|
DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138516
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|
PROTAC Linkers
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Cancer
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|
CG-PEG5-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . CG-PEG5-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140778
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|
PROTAC Linkers
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Cancer
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|
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140214
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140795
-
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140856
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-130507
-
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|
PROTAC Linkers
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Cancer
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|
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-133174
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|
PROTAC Linkers
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Cancer
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|
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140954
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|
|
PROTAC Linkers
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Cancer
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|
DSPE-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138738
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|
|
PROTAC Linkers
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Cancer
|
|
Propargyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140826
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|
|
PROTAC Linkers
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Cancer
|
|
Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromoacetamido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140744
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|
|
PROTAC Linkers
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Cancer
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|
Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-130168
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|
|
PROTAC Linkers
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Cancer
|
|
m-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-133392
-
|
|
PROTAC Linkers
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Cancer
|
|
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-134687
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|
PROTAC Linkers
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Cancer
|
|
Iodoacetamide-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140757
-
|
|
PROTAC Linkers
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Cancer
|
|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140159
-
|
|
PROTAC Linkers
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Cancer
|
|
Methylamino-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methylamino-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W022232
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-140634
-
|
|
ADC Linker
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Cancer
|
|
Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-130194
-
|
|
ADC Linker
PROTAC Linkers
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Cancer
|
|
Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130872
-
|
Thiol-PEG5-amine
|
PROTAC Linkers
|
Cancer
|
|
HS-PEG5-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140434
-
|
|
PROTAC Linkers
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Cancer
|
|
t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140769
-
|
|
PROTAC Linkers
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Cancer
|
|
Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-succinimidyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-132093
-
|
|
PROTAC Linkers
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Cancer
|
|
Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-S-methyl ethanethioate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140837
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-132111
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140352
-
|
|
ADC Linker
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Cancer
|
|
Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-130420
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-130872A
-
|
Thiol-PEG5-amine hydrochloride
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PROTAC Linkers
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Cancer
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|
HS-PEG5-CH2CH2NH2 hydrochloride is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules.
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-
- HY-W190985
-
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|
Biochemical Assay Reagents
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Others
|
|
AZD-PEG5-methyl ester is a PEG linker containing an AZD group and a methyl ester group which can be hydrolyzed under strong basic condition. The hydrophilic PEG spacer increases solubility in aqueous media.
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-
- HY-141040
-
|
|
PROTAC Linkers
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Cancer
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|
N-methyl-N'-methyl-O-(m-PEG4)-O'-(acid-PEG5)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-131959
-
-
- HY-141150
-
|
|
ADC Linker
|
Cancer
|
|
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-172720
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|
Biochemical Assay Reagents
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Others
|
|
Azide-PEG5-Ms serves as a PEG linker containing an azide that reacts with BCN, DBCO, alkyne via Click Chemistry and mesyl group that is a good leaving group for nucleophilic substitution reactions. The PEG spacer imparts water solubility.
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-
- HY-140766
-
|
|
PROTAC Linkers
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Cancer
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|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W800688
-
|
|
Biochemical Assay Reagents
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Others
|
|
Acid-PEG5-Amide-Tri(3-methoxypropanamide-PEG4-Azide) Methane is a branched PEG linker with a terminal carboxylic acid group and three terminal azides. The azide groups enables PEGylation via Click Chemistry.
|
-
- HY-W096068
-
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|
Biochemical Assay Reagents
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Others
|
|
Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.
|
-
- HY-130693
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130879
-
|
|
PROTAC Linkers
|
Cancer
|
|
HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HS-PEG5-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130957
-
|
|
ADC Linker
|
Cancer
|
|
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W800803
-
|
|
Biochemical Assay Reagents
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Others
|
|
Mal-PEG5-NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond.
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-
- HY-W190950
-
|
|
Biochemical Assay Reagents
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Others
|
|
AZD-PEG5-PFP is a PEG linker containing an AZD group and a PFP ester group, an activated ester that reacts with primary amines to form amide bonds. PFP ester has been found to be more stable than other amine reactive groups because it is less likely to undergo hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-176536
-
|
VH032-CO-(CH2)2-(O-CH2-CH2)5-azide
|
PROTAC Linkers
|
Cancer
|
|
(S,R,S)-AHPC-amide-PEG5-C2-azide (VH032-CO-(CH2)2-(O-CH2-CH2)5-azide) is a PROTAC linker that can be used to design PROTACs .
|
-
- HY-W800654
-
|
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Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W460275
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-N-Amido-PEG5-Tos is a PEG linker containing a tosyl group and Boc-protected amine group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.
|
-
- HY-W800670
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W800813
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Carboxy-Amido-PEG5-N-Boc is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-140821
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140822
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-137340
-
|
|
PROTACs
Casein Kinase
|
Cancer
|
|
WH-10417-099 is a CRBN-based PROTAC multi-kinase degrader that induces the degradation of the maximum number of unique kinases (over 125 unique kinases, such as CSNK1E and PI3Kγ) simultaneously. WH-10417-099 induces protein degradation via the ubiquitin biotinylation (E-STUB) pathway, exhibits synergistic effects with SB-405483 (HY-W1135319). The E3 ligase ligand and linker of WH-10417-099 can form the conjugate Pomalidomide 4'-PEG5-acid (HY-131647) .
|
-
- HY-155643
-
|
|
PROTACs
Glutaminase
|
Cancer
|
|
PROTAC TG2 degrader-1 (compound 11) is a von Hippel-Lindau (VHL)-based PROTAC targeting tissue transglutaminase (TG2) with a KD of 68.9 μM. PROTAC TG2 degrader-1 reduces TG2 in ovarian cancer cells in a proteasome-dependent manner .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2420
-
|
|
Fluorescent Dye
|
|
Biotin-PEG5-Mal is a PROTAC linker, belonging to the PEG class. It can be used for the synthesis of PROTAC molecules .
|
| Cat. No. |
Product Name |
Type |
| Cat. No. |
Product Name |
|
Classification |
-
- HY-141269
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140214
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-101157
-
|
|
|
PROTAC Synthesis
Alkynes
ADC Synthesis
|
|
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126885
-
|
|
|
DBCO
ADC Synthesis
PROTAC Synthesis
|
|
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130211
-
|
|
|
PROTAC Synthesis
Azide
ADC Synthesis
|
|
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130388
-
|
|
|
Alkynes
ADC Synthesis
PROTAC Synthesis
|
|
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140752
-
|
|
|
PROTAC Synthesis
Azide
|
|
DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130572
-
|
|
|
Azide
ADC Synthesis
PROTAC Synthesis
|
|
Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140757
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133392
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130147
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130551
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140352
-
|
|
|
ADC Synthesis
Azide
|
|
Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126976
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140314
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130957
-
|
|
|
ADC Synthesis
Azide
|
|
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130507
-
|
|
|
Azide
PROTAC Synthesis
|
|
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133174
-
|
|
|
PROTAC Synthesis
Azide
|
|
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134687
-
|
|
|
PROTAC Synthesis
Azide
|
|
Iodoacetamide-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140821
-
|
|
|
PROTAC Synthesis
Azide
|
|
Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140267
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133467
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG5-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-141059
-
|
|
|
Azide
PROTAC Synthesis
|
|
Cy5-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Cy5-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140753
-
|
|
|
PROTAC Synthesis
Azide
|
|
DOTA-(t-butyl)3-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-(t-butyl)3-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140856
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130420
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140766
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141275
-
|
|
|
Tetrazine
Alkynes
|
|
Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140302
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140826
-
|
|
|
PROTAC Synthesis
Azide
|
|
Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromoacetamido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-176536
-
|
VH032-CO-(CH2)2-(O-CH2-CH2)5-azide
|
|
Azide
|
|
(S,R,S)-AHPC-amide-PEG5-C2-azide (VH032-CO-(CH2)2-(O-CH2-CH2)5-azide) is a PROTAC linker that can be used to design PROTACs .
|
-
- HY-133193
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity . Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W1130361
-
|
|
|
Azide
|
|
(S,R,S)-AHPC-PEG5-Azide is a VHL ligand based on (S,R,S)-AHPC that recruits von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-PEG5-Azide can be linked to a target protein ligand via a linker to form a PROTACs.
|
-
- HY-141095
-
|
|
|
Alkynes
|
|
Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156493
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-133475
-
|
|
|
TCO
PROTAC Synthesis
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-140275
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W190931
-
|
|
|
Alkynes
|
|
Thalidomide-O-PEG5-alkyne is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
|
-
- HY-125541
-
|
|
|
ADC Synthesis
PROTAC Synthesis
DBCO
|
|
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136054
-
|
|
|
ADC Synthesis
Azide
|
|
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140778
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130168
-
|
|
|
PROTAC Synthesis
Azide
|
|
m-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130194
-
|
|
|
ADC Synthesis
PROTAC Synthesis
Azide
|
|
Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130879
-
|
|
|
Azide
PROTAC Synthesis
|
|
HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HS-PEG5-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-139333
-
|
|
|
Azide
|
|
Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-159777
-
|
|
|
Alkynes
|
|
CPI-203-PEG5-Alkyne is a conjugate of target protein ligase and linker. CPI-203-PEG5-Alkyne can be used for synthesis of PROTAC BRD4-DCAF1 degrader-1 (HY-169151) .
|
-
- HY-141283
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156490
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-132043
-
|
|
|
Alkynes
PROTAC Synthesis
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Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-138719
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Alkynes
PROTAC Synthesis
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m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-138736
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Alkynes
PROTAC Synthesis
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Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140958
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Alkynes
PROTAC Synthesis
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DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140046
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PROTAC Synthesis
Alkynes
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Propargyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141276
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Tetrazine
Alkynes
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Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-136140
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PROTAC Synthesis
Alkynes
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Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140053
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PROTAC Synthesis
Alkynes
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Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140880
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PROTAC Synthesis
Alkynes
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Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-133463
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PROTAC Synthesis
Tetrazine
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Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-Ph-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130945
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ADC Synthesis
Tetrazine
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Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-W096140
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Alkynes
PROTAC Synthesis
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Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140954
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PROTAC Synthesis
Azide
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DSPE-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138516
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Azide
PROTAC Synthesis
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CG-PEG5-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . CG-PEG5-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140795
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PROTAC Synthesis
Azide
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Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138738
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PROTAC Synthesis
Alkynes
Azide
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Propargyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140744
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PROTAC Synthesis
Azide
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Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140159
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PROTAC Synthesis
Azide
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Methylamino-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methylamino-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140634
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Azide
ADC Synthesis
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Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140434
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PROTAC Synthesis
Azide
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t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140769
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Azide
PROTAC Synthesis
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Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-succinimidyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132093
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Azide
PROTAC Synthesis
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Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-S-methyl ethanethioate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140837
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PROTAC Synthesis
Azide
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Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132111
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PROTAC Synthesis
Azide
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Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-141150
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Azide
ADC Synthesis
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Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W096068
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Alkynes
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Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.
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- HY-130693
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PROTAC Synthesis
Azide
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Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140822
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PROTAC Synthesis
Azide
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Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-129621
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Azide
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N3-PEG5-C6-Cl is a PEG PROTAC linker, can be used for synthesis of HALo PROTAC .
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- HY-140810
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Azide
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3-(Azido-PEG5-amino)propanol is a PEG linker which contains an azide moiety and a hydroxyl group. 3-(Azido-PEG5-amino)propanol is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.
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