t-Boc-N-amido-PEG5-acetic acid
Based on 1 Customer Validation
BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.33%
- CAS No.: 890152-41-7
- Formula: C17H33NO9
- Molecular Weight:395.45
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-42640
Boc-NH-PEG4-CH2COOH -
HY-140477
Boc-NH-PEG6-CH2COOH -
HY-33366
Boc-NH-PEG3-CH2COOH -
HY-42776
NH2-PEG3-C2-NH-Boc -
HY-W005056
Boc-NH-PEG2-CH2COOH -
HY-140476
Boc-NH-PEG1-CH2COOH -
HY-W004896
Boc-NH-PEG2 -
HY-140468
Boc-N-amido-PEG3-acid -
HY-140234
Boc-NH-PEG11-NH2 -
HY-W040132
Boc-NH-PEG4-CH2CH2COOH -
HY-140235
Boc-NH-PEG15-NH2 -
HY-W006445
N-Boc-PEG2-bromide
All PROTAC Linkers Isoforms
More
Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 890152-41-7
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Appearance Liquid (Density: 1.136±0.06 g/cm3)
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Molecular Weight 395.45
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Formula C17H33NO9
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Color Colorless to light yellow
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SMILES
O=C(NCCOCCOCCOCCOCCOCC(O)=O)OC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (252.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5288 mL | 12.6438 mL | 25.2876 mL | 63.2191 mL |
| 5 mM | 0.5058 mL | 2.5288 mL | 5.0575 mL | 12.6438 mL | |
| 10 mM | 0.2529 mL | 1.2644 mL | 2.5288 mL | 6.3219 mL | |
| 15 mM | 0.1686 mL | 0.8429 mL | 1.6858 mL | 4.2146 mL | |
| 20 mM | 0.1264 mL | 0.6322 mL | 1.2644 mL | 3.1610 mL | |
| 25 mM | 0.1012 mL | 0.5058 mL | 1.0115 mL | 2.5288 mL | |
| 30 mM | 0.0843 mL | 0.4215 mL | 0.8429 mL | 2.1073 mL | |
| 40 mM | 0.0632 mL | 0.3161 mL | 0.6322 mL | 1.5805 mL | |
| 50 mM | 0.0506 mL | 0.2529 mL | 0.5058 mL | 1.2644 mL | |
| 60 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL | |
| 80 mM | 0.0316 mL | 0.1580 mL | 0.3161 mL | 0.7902 mL | |
| 100 mM | 0.0253 mL | 0.1264 mL | 0.2529 mL | 0.6322 mL |
t-Boc-N-amido-PEG5-acetic acid Related Classifications
HY-W190962 Related Classifications
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