Boc-NH-PEG2-CH2COOH
Based on 1 Customer Validation
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 108466-89-3
- Formula: C11H21NO6
- Molecular Weight:263.29
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 108466-89-3
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Appearance Liquid (Density: 1.145±0.06 g/cm3)
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Molecular Weight 263.29
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Formula C11H21NO6
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Color Colorless to light yellow
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SMILES
CC(C)(C)OC(NCCOCCOCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (379.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7981 mL | 18.9905 mL | 37.9809 mL | 94.9523 mL |
| 5 mM | 0.7596 mL | 3.7981 mL | 7.5962 mL | 18.9905 mL | |
| 10 mM | 0.3798 mL | 1.8990 mL | 3.7981 mL | 9.4952 mL | |
| 15 mM | 0.2532 mL | 1.2660 mL | 2.5321 mL | 6.3302 mL | |
| 20 mM | 0.1899 mL | 0.9495 mL | 1.8990 mL | 4.7476 mL | |
| 25 mM | 0.1519 mL | 0.7596 mL | 1.5192 mL | 3.7981 mL | |
| 30 mM | 0.1266 mL | 0.6330 mL | 1.2660 mL | 3.1651 mL | |
| 40 mM | 0.0950 mL | 0.4748 mL | 0.9495 mL | 2.3738 mL | |
| 50 mM | 0.0760 mL | 0.3798 mL | 0.7596 mL | 1.8990 mL | |
| 60 mM | 0.0633 mL | 0.3165 mL | 0.6330 mL | 1.5825 mL | |
| 80 mM | 0.0475 mL | 0.2374 mL | 0.4748 mL | 1.1869 mL | |
| 100 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9495 mL |
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